Oxidative Stress Inflammatory Joint Diseases

#1 07-22-2008, 02:46 PM

"Confirms oxidative stress in the pathogenesis of RA."
"Antioxidant agents can potentially be a useful addition"

Protein oxidation markers in the serum and synovial fluid of psoriatic
arthritis patients.
Firuzi O, Spadaro A, Spadaro C, Riccieri V, Petrucci R, Marrosu G,
Saso L
J Clin Lab Anal 2008 May 16; 22(3):210-215.

The role of oxidative stress has been studied in rheumatoid arthritis
(RA) and other inflammatory joint diseases to some extent, but its
importance in psoriatic arthritis (PsA) has rarely been investigated.
The aim of this study was to analyze the levels of protein oxidation
markers, sulfhydryl (SH) and carbonyl (CO) groups, in the synovial
fluid (SF) and serum of PsA patients and compare them with the
findings in RA and osteoarthritis (OA) patients.
A total of 49 subjects with a knee-joint effusion including 16 PsA, 18
RA, and 15 OA patients were studied.
In all patients, the levels of SH groups measured in the serum and SF
inversely correlated with the number of white blood cells (WBC)
(P<0.05) and the percentage of polymorphonuclear leukocytes (PMN)
(P<0.01) in SF.
Serum SH levels inversely correlated with serum erythrocyte
sedimentation rate (ESR) (P<0.02) and C-reactive protein (CRP)
(P<0.05) values.
The SH levels in SF were significantly lower in patients affected by
PsA and RA compared to OA cases (P<0.02).
The serum SH levels in PsA were lower than OA (P<0.001) and higher
than RA patients (P<0.05).
The serum and synovial levels of CO groups in PsA, RA, and OA patients
were similar.
Our study provides novel evidence on the involvement of protein
oxidation in PsA and confirms the important role of oxidative stress
in the pathogenesis of RA.
These data suggest that antioxidant agents can potentially be a useful
addition to the conventional therapy in the management of these
diseases.
J. Clin. Lab. Anal. 22:210-215, 2008. (c) 2008 Wiley-Liss, Inc.

Journal of clinical laboratory analysis [J Clin Lab Anal]

--------------------------------------------------------------------------------

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

#2 07-22-2008, 11:49 PM

On Jul 22, 4:15*am, ironjustice <teamtan...@hotmail.com> wrote:
> "Confirms oxidative stress in the pathogenesis of RA."
> *"Antioxidant agents can potentially be a useful addition"
>
> Protein oxidation markers in the serum and synovial fluid of psoriatic
> arthritis patients.
> Firuzi O, Spadaro A, Spadaro C, Riccieri V, Petrucci R, Marrosu G,
> Saso L
> J Clin Lab Anal 2008 May 16; 22(3):210-215.
>
> The role of oxidative stress has been studied in rheumatoid arthritis
> (RA) and other inflammatory joint diseases to some extent, but its
> importance in psoriatic arthritis (PsA) has rarely been investigated.
> The aim of this study was to analyze the levels of protein oxidation
> markers, sulfhydryl (SH) and carbonyl (CO) groups, in the synovial
> fluid (SF) and serum of PsA patients and compare them with the
> findings in RA and osteoarthritis (OA) patients.
> A total of 49 subjects with a knee-joint effusion including 16 PsA, 18
> RA, and 15 OA patients were studied.
> In all patients, the levels of SH groups measured in the serum and SF
> inversely correlated with the number of white blood cells (WBC)
> (P<0.05) and the percentage of polymorphonuclear leukocytes (PMN)
> (P<0.01) in SF.
> Serum SH levels inversely correlated with serum erythrocyte
> sedimentation rate (ESR) (P<0.02) and C-reactive protein (CRP)
> (P<0.05) values.
> The SH levels in SF were significantly lower in patients affected by
> PsA and RA compared to OA cases (P<0.02).
> The serum SH levels in PsA were lower than OA (P<0.001) and higher
> than RA patients (P<0.05).
> The serum and synovial levels of CO groups in PsA, RA, and OA patients
> were similar.
> Our study provides novel evidence on the involvement of protein
> oxidation in PsA and confirms the important role of oxidative stress
> in the pathogenesis of RA.
> These data suggest that antioxidant agents can potentially be a useful
> addition to the conventional therapy in the management of these
> diseases.
> J. Clin. Lab. Anal. 22:210-215, 2008. (c) 2008 Wiley-Liss, Inc.
>
> Journal of clinical laboratory analysis [J Clin Lab Anal]
>
> ---------------------------------------------------------------------------*-----
>
Tom= REALLY A HERMAPHRODITIC NEANDERTHAL THAT WILL NOT GO AWAY.

Jesus Was A Vegetarian! JESUS ATE FISH. HE ATE A MEDITERRANEAN DIET.
http://tinyurl.com/2r2nkh (WHY ARE YOU ADVERTISING THAT YOU HAVE A
TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)

Man Is A Herbivore! I AM MAN, I AM HUMAN, I EAT MEAT. MOST PEOPLE EAT
MEAT AND ARE NOT HERBIVORES!
http://tinyurl.com/4rq595 (WHY ARE YOU ADVERTISING THAT YOU HAVE A
TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)

DEAD PEOPLE WALKING. DEAD PEOPLE CANNOT TALK, WALK, OR EAT,
REGARDLESS
OF THE BULLSHIT SWIMMING AROUND IN THAT FILTHY, SICK, ANNOYING HEAD
OF
YOURS.
http://tinyurl.com/zk9fk (WHY ARE YOU ADVERTISING THAT YOU HAVE A
TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)

STAY OFF ANY THREADS.
HOW DO YOU OWN ANYTHING?
STAY OUT OF THE NEWSGROUPS.
QUIT POSTING NONSENSE THAT NO ONE WANTS TO HEAR.
THE ONLY PURPOSE YOU HAVE IN LIFE IS TO ANNOY THOSE ACTUALLY USING
THESE SERVICES FOR THE INTENDED PURPOSE BY POSTING YOUR SHIT.
QUIT.

YOU FIT THE PROFILE OF THE CYBERSTALKER, CYBERBULLY. YOU ARE THE ONE
and ONLY PERSON DOING THAT TO THE REST OF THE NEWSGROUP SUBSCRIBERS.

GO AWAY.

WHY CAN'T YOU UNDERSTAND THAT **YOUR POSTING IS NOT WANTED HERE*****

#3 07-23-2008, 04:34 AM

On Jul 22, 2:32*pm, aka_velcro <Crystalarev...@gmail.com> wrote: snip
<<

Remember do not break crush chew or inject those meds.

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

> On Jul 22, 4:15*am, ironjustice <teamtan...@hotmail.com> wrote:
>
>
>
> > "Confirms oxidative stress in the pathogenesis of RA."
> > *"Antioxidant agents can potentially be a useful addition"
>
> > Protein oxidation markers in the serum and synovial fluid of psoriatic
> > arthritis patients.
> > Firuzi O, Spadaro A, Spadaro C, Riccieri V, Petrucci R, Marrosu G,
> > Saso L
> > J Clin Lab Anal 2008 May 16; 22(3):210-215.
>
> > The role of oxidative stress has been studied in rheumatoid arthritis
> > (RA) and other inflammatory joint diseases to some extent, but its
> > importance in psoriatic arthritis (PsA) has rarely been investigated.
> > The aim of this study was to analyze the levels of protein oxidation
> > markers, sulfhydryl (SH) and carbonyl (CO) groups, in the synovial
> > fluid (SF) and serum of PsA patients and compare them with the
> > findings in RA and osteoarthritis (OA) patients.
> > A total of 49 subjects with a knee-joint effusion including 16 PsA, 18
> > RA, and 15 OA patients were studied.
> > In all patients, the levels of SH groups measured in the serum and SF
> > inversely correlated with the number of white blood cells (WBC)
> > (P<0.05) and the percentage of polymorphonuclear leukocytes (PMN)
> > (P<0.01) in SF.
> > Serum SH levels inversely correlated with serum erythrocyte
> > sedimentation rate (ESR) (P<0.02) and C-reactive protein (CRP)
> > (P<0.05) values.
> > The SH levels in SF were significantly lower in patients affected by
> > PsA and RA compared to OA cases (P<0.02).
> > The serum SH levels in PsA were lower than OA (P<0.001) and higher
> > than RA patients (P<0.05).
> > The serum and synovial levels of CO groups in PsA, RA, and OA patients
> > were similar.
> > Our study provides novel evidence on the involvement of protein
> > oxidation in PsA and confirms the important role of oxidative stress
> > in the pathogenesis of RA.
> > These data suggest that antioxidant agents can potentially be a useful
> > addition to the conventional therapy in the management of these
> > diseases.
> > J. Clin. Lab. Anal. 22:210-215, 2008. (c) 2008 Wiley-Liss, Inc.
>
> > Journal of clinical laboratory analysis [J Clin Lab Anal]
>
> > ---------------------------------------------------------------------------**-----
>
> Tom= REALLY A HERMAPHRODITIC NEANDERTHAL THAT WILL NOT GO AWAY.
>
> Jesus Was A Vegetarian! JESUS ATE FISH. HE ATE A MEDITERRANEAN DIET.http://tinyurl.com/2r2nkh(WHY ARE YOU ADVERTISING THAT YOU HAVE A
> TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
> AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)
>
> Man Is A Herbivore! I AM MAN, I AM HUMAN, I EAT MEAT. MOST PEOPLE EAT
> MEAT AND ARE NOT HERBIVORES!http://tinyurl.com/4rq595(WHY ARE YOU ADVERTISING THAT YOU HAVE A
> TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
> AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)
>
> DEAD PEOPLE WALKING. DEAD PEOPLE CANNOT TALK, WALK, OR EAT,
> REGARDLESS
> OF THE BULLSHIT SWIMMING AROUND IN THAT FILTHY, SICK, ANNOYING HEAD
> OF
> YOURS.http://tinyurl.com/zk9fk(WHY ARE YOU ADVERTISING THAT YOU HAVE A
> TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
> AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)
>
> STAY OFF ANY THREADS.
> HOW DO YOU OWN ANYTHING?
> STAY OUT OF THE NEWSGROUPS.
> QUIT POSTING NONSENSE THAT NO ONE WANTS TO HEAR.
> THE ONLY PURPOSE YOU HAVE IN LIFE IS TO ANNOY THOSE ACTUALLY USING
> THESE SERVICES FOR THE INTENDED PURPOSE BY POSTING YOUR SHIT.
> QUIT.
>
> YOU FIT THE PROFILE OF THE CYBERSTALKER, CYBERBULLY. YOU ARE THE ONE
> and ONLY PERSON DOING THAT TO THE REST OF THE NEWSGROUP SUBSCRIBERS.
>
> GO AWAY.
>
> WHY CAN'T YOU UNDERSTAND THAT **YOUR POSTING IS NOT WANTED HERE*****- Hide quoted text -
>
> - Show quoted text -