>> On Sep 24, 1:14 pm, Nikki <wildthang_...@hotmail.com> wrote:but nothing is working.
thanks <<
Vegetarian diet and you have to go after the iron which is causing the
problems ..
The link is the diet and the following articles show the recovery
which is afforded by going AFTER the iron ..
http://www.ajcn.org/cgi/content/full/70/3/594S {vegetarian diet for
rheumatoid arthritis]
Ann Rheum Dis 1989 May;48(5):382-8
Investigation of the anti-inflammatory properties of
hydroxypyridinones.
Hewitt SD, Hider RC, Sarpong P, Morris CJ, Blake DR
Cancer Research Unit, University of York, Heslington.
Synovial iron deposition associated with rheumatoid disease may
result
in the production of highly reactive oxygen free radicals, leading
to
tissue damage. This chain of events can be interrupted by iron
chelation. Families of strong iron (III) chelators have been
tested
for their iron scavenging properties in vitro and their effects
assessed in vivo using a rat model of inflammation. All the
chelators
competed successfully for iron with apotransferrin, and some
removed
up to 34% of iron from ferritin. The best anti-inflammatory
effects
were achieved with the most hydrophilic chelators and those which
chelated iron most avidly. Activity was dependent on dose. The
route
of administration was also an important factor with lower affinity
chelators. This work introduces a range of simple bidentate iron
chelators, which under certain conditions exceed desferrioxamine
in
their iron scavenging abilities, and some of which, in this simple
animal model, approach indomethacin in their anti-inflammatory
capabilities.
Comments:
* Comment in: Ann Rheum Dis 1990 Nov;49(11):956-7
PMID: 2730166, UI: 89272259
__________________________________________________ _______________
Original Article
Treatment of hemophilic arthritis with D-penicillamine: A preliminary
report
Dr. James J. Corrigan Jr. 1 3 5 *, Karen S. Kolba 4, Eric P. Gall 2
4,
Joyce Trombley 4, Mary Lou Damiano 5, Keith Meredith 6, Monette Jeter
7
1Departments of Pediatrics, University of Arizona Health Sciences
Center, Tucson
2Departments of Internal Medicine, University of Arizona Health
Sciences Center, Tucson
3Departments of Sections of Pediatric Hematology-Oncology, University
of Arizona Health Sciences Center, Tucson
4Departments of Rheumatology, Allergy, and Immunology, University of
Arizona Health Sciences Center, Tucson
5Mountain States Regional Hemophilia Center, University of Arizona
Health Sciences Center, Tucson
6Southwest Arthritis Center, University of Arizona Health Sciences
Center, Tucson
7Coagulation Research Laboratory, University of Arizona Health
Sciences Center, Tucson
*Correspondence to James J. Corrigan Jr., Professor of Pediatrics,
Director, Mountain States Regional Hemophilia Center, University of
Arizona Health Sciences Center, Tucson AZ 85724
Funded by:
Thrasher Research Funds
National Hemophilia Foundation
Keywords
hemophilia · synovitis · rabbits · D-penicillamine
Abstract
Current medical management programs for established joint diseases in
hemophiliacs are unsatisfactory and do not modify the eventual
outcome. D-penicillamine, a drug effective in the proliferative
synovitis of rheumatoid arthritis, was evaluated in a rabbit model of
hemarthroses-induced arthritis and in four hemophiliacs with chronic
synovitis. The animals had intra-articular injections of citrate
(left
knees) and autologous citrated whole blood (right knees). Eight weeks
later, the rabbits were divided into two groups: no treatment and D-
penicillamine (50 mg/kg/day, IM) until sacrificed at 6 months. The
saline-injected joints showed no inflammation and no iron deposition.
The blood-injected knees showed iron deposition in both groups, the
D-
penicillamine animals had marked suppression of chronic inflammation.
Of the four patients treated, three had clinical responses (reduction
in synovial thickness, reduction in number of bleeds in the affected
joint). One patient, who did not respond, developed mild-moderate
proteinuria. Those patients who responded received between 5.3 and
7.1
mg/kg/day of the drug. Mild abnormalities in platelet aggregation
were
seen in the responders. This preliminary study suggests that D-
penicillamine is beneficial in the chronic synovitis/arthritis
induced
by hemarthroses. Further trials are recommended.
Received: 13 August 1984; Accepted: 25 October 1984
Digital Object Identifier (DOI)
---------------------------------------------------------------------------*-----
http://tinyurl.com/28r997
PENICILLAMINE CAPSULES
Indication
Antidote to heavy metals (chelating agent).
Penicillamine is a heavy metal antagonist that chelates copper,
iron,mercury, lead, and probably other heavy metals as well as
cystine*.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk 
Painful Bones 
Linear Mode
