STUDY: Fibrosarcoma after silicone breast augmentation: is there a connection?

From Health Lover, Ilena Rosenthal

www.BreastImplantAwareness.org/
http://ilenarose.blogspot.com


Harefuah. 1998 Mar 1;134(5):339-41, 424.

http://www.ncbi.nlm.nih.gov/pubmed/10909545?ordinalpos=1&itool=EntrezSystem2.PEntrez. Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.P ubmed_Discovery_RA&linkpos=2&log$=relatedarticles& dbfrom=pubmed
[Fibrosarcoma after silicone breast augmentation: is there a
connection?]
[Article in Hebrew]

Aharon-Maor A, Levy Y, Schoenfeld Y.

Medical Dept. B, Chaim Sheba Medical Center.

We describe a 42-year-old woman in whom bilateral fibrosarcoma of
the breast was diagnosed 15 years after bilateral breast augmentation
with silicone implants. 3 years prior to admission the implants were
replaced and 2 years prior to admission mammography showed a nodule in
the left breast which biopsy showed to be fibrosarcoma. The implants
were removed from both breasts and she was given chemotherapy but
later that year underwent bilateral mastectomy. Despite chemotherapy,
as well as adjuvant radiotherapy, the disease progressed, with
involvement of the lungs and the skin of the left hemithorax. She was
admitted repeatedly for severe anemia caused by bleeding from the
malignant skin lesions, and died less than 2 years after diagnosis of
the disease. Not all reports in the literature find a significant
connection between silicone implants and subsequent development of
breast cancer, but there are reports that do connect them. Breast
fibrosarcoma is not significantly more frequent after silicone
augmentation, but still there is controversy as to whether there is a
connection between silicone implants and breast malignancy. In the
patient we present, the prolonged exposure to silicone may have been a
predisposing factor for the development of bilateral fibrosarcoma,
since other known risk factors for breast cancer were denied.