RT with/without ADT: GI & GU toxicity

*With* seems better.

See Lawton CA, et al., "Long-term treatment sequelae after external beam
irradiation with or without hormonal manipulation for adenocarcinoma of
the prostate: analysis of radiation therapy oncology group studies
85-31, 86-10, and 92-02." Int J Radiat Oncol Biol Phys. 2008 Feb
1;70(2):437-41.

"CONCLUSIONS: These data show that external beam radiation therapy
remains a safe option for locally advanced/high-risk prostate cancer,
and the use of hormonal manipulation does appear to be protective for GU
and GI toxicity depending upon length of treatment."

Pub Med ID: 17881145. Pub Med, a service of the US National Library of
Medicine, is at www.pubmed.gov

(GI = gastrointestinal; GU = genitourinary)

Regards,

Steve J