Cancer predisposition question

As many of you who follow this NG know, I am a CRC stage 4 patient.
FYI my younger brother got stomach cancer after my own diagnosis and
died shortly afterwards. Today I find out that my other younger
brother has prostate cancer early stages, fortunately). Sheesh! Is
this just a coincidence? Is predisposition limited to only same-type
cancers?

46erjoe wrote:
> As many of you who follow this NG know, I am a CRC stage 4 patient.
> FYI my younger brother got stomach cancer after my own diagnosis and
> died shortly afterwards. Today I find out that my other younger
> brother has prostate cancer early stages, fortunately). Sheesh! Is
> this just a coincidence? Is predisposition limited to only same-type
> cancers?

I can't answer that. But my father had epiglottis cancer and then lung
cancer, and I had epiglottis cancer and then lung cancer. The oldest of
my siblings only made it to age 39, so no other data.

--
Asking Iran and Syria to help us succeed in Iraq is like your local fire
department asking a couple of arsonists to help put out the fire.
-- Joe Lieberman

"46erjoe" <somebody@spamless.net> wrote in message
news:uitbn2lh1hjdveqb3u3l5ggva90h5t6e0e@4ax.com...
> As many of you who follow this NG know, I am a CRC stage 4 patient.
> FYI my younger brother got stomach cancer after my own diagnosis and
> died shortly afterwards. Today I find out that my other younger
> brother has prostate cancer early stages, fortunately). Sheesh! Is
> this just a coincidence? Is predisposition limited to only same-type
> cancers?

It's almost certainly just a coincidence.
There are families with genetic DNA repair problems, and they have an
increased risk of cancers. You three simply have 3 common
cancers..............

46erjoe wrote:
> As many of you who follow this NG know, I am a CRC stage 4 patient.
> FYI my younger brother got stomach cancer after my own diagnosis and
> died shortly afterwards. Today I find out that my other younger
> brother has prostate cancer early stages, fortunately). Sheesh! Is
> this just a coincidence? Is predisposition limited to only same-type
> cancers?

Not as I've been told. When I gave the cancer docs my own history: dad
with non-hotchkins lymphoma, maternal uncle with pancreatic cancer,
maternal aunt with lung cancer, maternal aunt with stomach cancer, one
(matrnal)first cousin with breast cancer and another, her brother, first
cousin with a virulent form of lukemia, they told me it was not a
question of 'when' I would get cancer, just 'where' I would get it.

One of the oncologists put it quite succintly when he said that 7 people
in his immediate family had cancer and he didn't have it *yet*.

--
Janet Wilder
Bad spelling. Bad punctuation
Good Friends. Good Life

My experience was similar to yours Janet. I was asked for an extensive
family medical history.
The answer I was told the researchers are still trying to calculate cancer
risk. Some risk could be environmental which a family shares.

Although the genetic counselor doesn't use this in cancer risk prevention, I
know they are tracking patterns for research. I was told the more data they
collect the more they will learn.

"Janet Wilder" <kelliepoodle@yahoo.com> wrote in message
news:45770035$0$30599$c3e8da3@news.astraweb.com...
> 46erjoe wrote:
>> As many of you who follow this NG know, I am a CRC stage 4 patient.
>> FYI my younger brother got stomach cancer after my own diagnosis and
>> died shortly afterwards. Today I find out that my other younger
>> brother has prostate cancer early stages, fortunately). Sheesh! Is
>> this just a coincidence? Is predisposition limited to only same-type
>> cancers?
>
> Not as I've been told. When I gave the cancer docs my own history: dad
> with non-hotchkins lymphoma, maternal uncle with pancreatic cancer,
> maternal aunt with lung cancer, maternal aunt with stomach cancer, one
> (matrnal)first cousin with breast cancer and another, her brother, first
> cousin with a virulent form of lukemia, they told me it was not a question
> of 'when' I would get cancer, just 'where' I would get it.
>
> One of the oncologists put it quite succintly when he said that 7 people
> in his immediate family had cancer and he didn't have it *yet*.
>
> --
> Janet Wilder
> Bad spelling. Bad punctuation
> Good Friends. Good Life