Cisplatin for Palliative care ?

Relative in Germany had bladder cancer. Was told that the scrapings
and washes (a Chemo wash) worked and there was no longer a sign of
cancer cells in the bladder. Now, a couple of years later, extreme
pain. "Hausarzt" -( PC, I guess, but he never goes to hospital) was
coming 3 or 4 times a day to give injections for pain. Could not find
a reason for the pain. Then another MD inserted a Port. At that time
it was discovered that the CA had spread to the lung. Subsequently
had a scan....CA is in lung, abdomen and bones. Sent to hospital for
more tests and course of treatment. They have prescribed Cisplatin "a
weak cisplatin" as palliative. I am not sure I understand this. I
see that Cisplatin is used for advanced bladder cancer. Will it also
effect the pain which I would assume is from the bone metastesis? I
do know the MD there told his family "maybe a few months."

sheder1 wrote:

> Relative in Germany had bladder cancer. Was told that the scrapings
> and washes (a Chemo wash) worked and there was no longer a sign of
> cancer cells in the bladder. Now, a couple of years later, extreme
> pain. "Hausarzt" -( PC, I guess, but he never goes to hospital) was
> coming 3 or 4 times a day to give injections for pain. Could not find
> a reason for the pain. Then another MD inserted a Port. At that time
> it was discovered that the CA had spread to the lung. Subsequently
> had a scan....CA is in lung, abdomen and bones. Sent to hospital for
> more tests and course of treatment. They have prescribed Cisplatin "a
> weak cisplatin" as palliative. I am not sure I understand this. I
> see that Cisplatin is used for advanced bladder cancer. Will it also
> effect the pain which I would assume is from the bone metastesis? I
> do know the MD there told his family "maybe a few months."

Since they can't find the source of pain, cisplatin sounds reasonable to
try.
http://jco.ascopubs.org/cgi/content/full/17/9/2876
"Cisplatin is generally considered to be the most active agent against
this disease"
I think somewhere in there it said it was more tolerable (unless there's a
hypersensitivity reaction or renal impairment; mentioned in the one below
- which I have not fully read.
J

http://www.viha.ca/NR/rdonlyres/46C3...cisplatin2.pdf.

On Sep 12, 11:08*am, J <xewsnswex@nalid;"no> wrote:
> sheder1 wrote:
> > Relative in Germany had bladder cancer. *Was told that the scrapings
> > and washes (a Chemo wash) worked and there was no longer a sign of
> > cancer cells in the bladder. *Now, a couple of years later, extreme
> > pain. *"Hausarzt" -( PC, I guess, but he never goes to hospital) was
> > coming 3 or 4 times a day to give injections for pain. *Could not find
> > a reason for the pain. *Then another MD inserted a Port. *At that time
> > it was discovered that the CA had spread to the lung. * Subsequently
> > had a scan....CA is in lung, abdomen and bones. *Sent to hospital for
> > more tests and course of treatment. *They have prescribed Cisplatin "a
> > weak cisplatin" as palliative. * I am not sure I understand this. *I
> > see that Cisplatin is used for advanced bladder cancer. *Will it also
> > effect the pain which I would assume is from the bone metastesis? * I
> > do know the MD there told his family "maybe a few months."
>
> Since they can't find the source of pain, cisplatin sounds reasonable to
> try.http://jco.ascopubs.org/cgi/content/full/17/9/2876
> "Cisplatin is generally considered to be the most active agent against
> this disease"
> I think somewhere in there it said it was more tolerable (unless there's a
> hypersensitivity reaction or renal impairment; mentioned in the one below
> - which I have not fully read.
> J
>
> http://www.viha.ca/NR/rdonlyres/46C3...-67C75F66FC62/....

I guess I did not make it clear. The source of the pain was unknown
until they discovered the bone involvement. I have read several and
many sites for Cisplatin and have yet to see "Palliative." That
remains my question.

sheder1 wrote:

> On Sep 12, 11:08 am, J <xewsnswex@nalid;"no> wrote:
> > sheder1 wrote:
> > > Relative in Germany had bladder cancer. Was told that the scrapings
> > > and washes (a Chemo wash) worked and there was no longer a sign of
> > > cancer cells in the bladder. Now, a couple of years later, extreme
> > > pain. "Hausarzt" -( PC, I guess, but he never goes to hospital) was
> > > coming 3 or 4 times a day to give injections for pain. Could not find
> > > a reason for the pain. Then another MD inserted a Port. At that time
> > > it was discovered that the CA had spread to the lung. Subsequently
> > > had a scan....CA is in lung, abdomen and bones. Sent to hospital for
> > > more tests and course of treatment. They have prescribed Cisplatin "a
> > > weak cisplatin" as palliative. I am not sure I understand this. I
> > > see that Cisplatin is used for advanced bladder cancer. Will it also
> > > effect the pain which I would assume is from the bone metastesis? I
> > > do know the MD there told his family "maybe a few months."
> >
> > Since they can't find the source of pain, cisplatin sounds reasonable to
> [snip]
>
> I guess I did not make it clear. The source of the pain was unknown
> until they discovered the bone involvement. I have read several and
> many sites for Cisplatin and have yet to see "Palliative." That
> remains my question.

Radotherapy is probably preferable to chemo for bone pain, but unlikely they'd
do both together, since one potentiates the other; so one would have to know
their goal of the chemo and whether your relative has had a consult with a
radiation oncologist and why chemo was chosen. I assume nothing; details are
important.
J

"sheder1" wrote:
>
> I guess I did not make it clear. The source of the pain was unknown until
> they discovered the bone involvement. I have read several and many sites
> for Cisplatin and have yet to see "Palliative." That remains my question.

Here's one:
http://content.karger.com/ProdukteDB....asp?Doi=81336

Also, when I was recently told that my cancer is terminal, the doctor
indicated palliative treatment would likely include Cisplatin and another
drug. However, now that I'm in an experimental research program, other drugs
have been selected.

Regards,
Robert