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  #1  
Old 04-01-2007, 11:14 AM
Matti Narkia
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Default Ketamine reduces incidence of dry mouth in patients with cancer?

The title of the article

Mogos M, Thangathurai D, Roffey P.
Low incidence of dry mouth in patients with cancer with the use of
ketamine.
J Palliat Med. 2007 Feb;10(1):6.
PMID: 17298243 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlu s&list_uids=17298243>

seems to suggest that ketamine
(<http://en.wikipedia.org/wiki/Ketamine>) may help to reduce the
incidence of dry mouth in cancer patients. Unfortunaly there is no
asbtract, and the article itself is restricted to the subscribers and
paying customers. Has anyone access to the article?



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Matti Narkia
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  #2  
Old 04-02-2007, 01:43 AM
J
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Default Re: Ketamine reduces incidence of dry mouth in patients with cancer?

Matti Narkia wrote:

> The title of the article
>
> Mogos M, Thangathurai D, Roffey P.
> Low incidence of dry mouth in patients with cancer with the use of
> ketamine.
> J Palliat Med. 2007 Feb;10(1):6.
> PMID: 17298243 [PubMed - indexed for MEDLINE]
> <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlu s&list_uids=17298243>
>
> seems to suggest that ketamine
> may help to reduce the incidence of dry mouth in cancer patients.


No. It's saying that it has less dry mouth as a side effect.
It's a general anesthetic; used by veterinarians; used in palliative care in some instances and/or countries.
It's street drug; date rape drug.http://tinyurl.com/2umplw
J

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  #3  
Old 04-02-2007, 01:43 AM
Uncle Sally
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Default Re: Ketamine reduces incidence of dry mouth in patients with cancer?

"Matti Narkia" wrote :

.... snip ...

"<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlu s&list_uids=17298243>

seems to suggest that ketamine (<http://en.wikipedia.org/wiki/Ketamine>) may
help to reduce the incidence of dry mouth in cancer patients. Unfortunaly
there is no asbtract, and the article itself is restricted to the
subscribers and paying customers. Has anyone access to the article?"

I think that using a dis-associative hallucinogenic anaesthetic would be
quite dangerous. This is the drug, I recall, that Dr. John Lilly used to
turn himself into a mental vegetable, joining other distinguished
self-medicating luminaries, such as Dr. Tim Leary, who had arrived at
neurological melt-downs before him, or in parallel with him.

Now if the study said that very low doses, which did not have the effects
for which "Special K" is famous for, or doses in combinaton with
anti-psychotic medications worked absolute miracles with dry mouth : I would
hope research would continue.

I wouldn't let a vet use it on my cat, either

best, Uncle Sally.



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  #4  
Old 04-02-2007, 01:43 AM
Matti Narkia
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Default Re: Ketamine reduces incidence of dry mouth in patients with cancer?

On Sun, 01 Apr 2007 12:23:39 -0400, J <nexsw@nvalid,anon> wrote:

>Matti Narkia wrote:
>
>> The title of the article
>>
>> Mogos M, Thangathurai D, Roffey P.
>> Low incidence of dry mouth in patients with cancer with the use of
>> ketamine.
>> J Palliat Med. 2007 Feb;10(1):6.
>> PMID: 17298243 [PubMed - indexed for MEDLINE]
>> <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlu s&list_uids=17298243>
>>
>> seems to suggest that ketamine
>> may help to reduce the incidence of dry mouth in cancer patients.

>
>No. It's saying that it has less dry mouth as a side effect.


In other words it _does_ help to reduce the incidence of dry mouth in
cancer patients. Whether it should be used solely for this purpose is
a different issue - probably not, at least not yet.




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Matti Narkia
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  #5  
Old 04-03-2007, 08:07 PM
Mike Radcliffe
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Default Re: Ketamine reduces incidence of dry mouth in patients with cancer?

>
> Mogos M, Thangathurai D, Roffey P.
> Low incidence of dry mouth in patients with cancer with the use of
> ketamine.
> J Palliat Med. 2007 Feb;10(1):6.
> PMID: 17298243 [PubMed - indexed for MEDLINE]
> <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlu s&list_uids=17298243>
>
> seems to suggest that ketamine
> (<http://en.wikipedia.org/wiki/Ketamine>) may help to reduce the
> incidence of dry mouth in cancer patients. Unfortunaly there is no
> asbtract, and the article itself is restricted to the subscribers and
> paying customers. Has anyone access to the article?>
> --
> Matti Narkia


Water reduces dry mouth in all situations and has no side effects.
Ketamine is a potentially very dangerous drug and is usually only used in
hospital in-patient situations under strict medical supervision.
MIKE


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