Question for Stephen or other's famiar with resumption of treatment

This is a question that I'm sure sure I've seen answered here or
anywhere else on the web. It has to do with resumption of treatment
after a long period away from it.

I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
irinotecan etc. No radiation though.

As of my last scan, tumors where held in check - no growth, some
shrinkage. So my onc took my off treatment to give me a break - 10
weeks perhaps.

My question is this: If my next scan shows growth, will it be of any
use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
has "shot its load" is it no longer effective? I'm wondering if, after
2 years away from a particular regimen, the body/tumors have changed
such that the first regimen can be helpful again.

Thanks

"46erjoe" <somebody@spamless.net> wrote in message
news:en9hk29lb8e2qgfpmvek9p9hpl44icqbpa@4ax.com...
> This is a question that I'm sure sure I've seen answered here or
> anywhere else on the web. It has to do with resumption of treatment
> after a long period away from it.
>
> I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
> irinotecan etc. No radiation though.
>
> As of my last scan, tumors where held in check - no growth, some
> shrinkage. So my onc took my off treatment to give me a break - 10
> weeks perhaps.
>
> My question is this: If my next scan shows growth, will it be of any
> use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
> has "shot its load" is it no longer effective? I'm wondering if, after
> 2 years away from a particular regimen, the body/tumors have changed
> such that the first regimen can be helpful again.
>
> Thanks

It's likely to be less effective if the tumour has seen it before.
The real question is what are you hoping treatment can achieve if you have
no symptoms

On Wed, 01 Nov 2006 15:10:09 GMT, "Steph" <steph@vancouvers.island>
wrotF:

>
>"46erjoe" <somebody@spamless.net> wrote in message
>news:en9hk29lb8e2qgfpmvek9p9hpl44icqbpa@4ax.com.. .
>> This is a question that I'm sure sure I've seen answered here or
>> anywhere else on the web. It has to do with resumption of treatment
>> after a long period away from it.
>>
>> I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
>> irinotecan etc. No radiation though.
>>
>> As of my last scan, tumors where held in check - no growth, some
>> shrinkage. So my onc took my off treatment to give me a break - 10
>> weeks perhaps.
>>
>> My question is this: If my next scan shows growth, will it be of any
>> use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
>> has "shot its load" is it no longer effective? I'm wondering if, after
>> 2 years away from a particular regimen, the body/tumors have changed
>> such that the first regimen can be helpful again.
>>
>> Thanks
>
>It's likely to be less effective if the tumour has seen it before.
>The real question is what are you hoping treatment can achieve if you have
>no symptoms
>


Thanks. I suspected that after treatments, tumors eventually "get
smart"and are no longer affected by the chemo. I was hoping though
that they "forget" after a while and previous treatments would be
affective again. I'm hoping of course for life extension. The symptoms
thusfar are only visible on scans and that any treatments whether old
or new will retart tumor growth.

I appreciate your presence in this group and the more technical info
you give us. Your time must be at a premium, so thanks from all of us.

"46erjoe" <somebody@spamless.net> wrote in message
news:f9shk21l2h083fp1g0qjh0t1esnjlkktv4@4ax.com...
> On Wed, 01 Nov 2006 15:10:09 GMT, "Steph" <steph@vancouvers.island>
> wrotF:
>
>>
>>"46erjoe" <somebody@spamless.net> wrote in message
>>news:en9hk29lb8e2qgfpmvek9p9hpl44icqbpa@4ax.com. ..
>>> This is a question that I'm sure sure I've seen answered here or
>>> anywhere else on the web. It has to do with resumption of treatment
>>> after a long period away from it.
>>>
>>> I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
>>> irinotecan etc. No radiation though.
>>>
>>> As of my last scan, tumors where held in check - no growth, some
>>> shrinkage. So my onc took my off treatment to give me a break - 10
>>> weeks perhaps.
>>>
>>> My question is this: If my next scan shows growth, will it be of any
>>> use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
>>> has "shot its load" is it no longer effective? I'm wondering if, after
>>> 2 years away from a particular regimen, the body/tumors have changed
>>> such that the first regimen can be helpful again.
>>>
>>> Thanks
>>
>>It's likely to be less effective if the tumour has seen it before.
>>The real question is what are you hoping treatment can achieve if you have
>>no symptoms
>>
>
>
> Thanks. I suspected that after treatments, tumors eventually "get
> smart"and are no longer affected by the chemo. I was hoping though
> that they "forget" after a while and previous treatments would be
> affective again. I'm hoping of course for life extension. The symptoms
> thusfar are only visible on scans and that any treatments whether old
> or new will retart tumor growth.
>

There is unfortunately very little evidence that treatment in your
circumstances will produce any survival extension. You may suffer
side-effects for no benefit.

> I appreciate your presence in this group and the more technical info
> you give us. Your time must be at a premium, so thanks from all of us.

Steph wrote:

> "46erjoe" <somebody@spamless.net> wrote in message
> > On Wed, 01 Nov 2006 15:10:09 GMT, "Steph" <steph@vancouvers.island>
> > wrotF:
> >
> >>
> >>"46erjoe" <somebody@spamless.net> wrote in message
> >>> This is a question that I'm sure sure I've seen answered here or
> >>> anywhere else on the web. It has to do with resumption of treatment
> >>> after a long period away from it.
> >>>
> >>> I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
> >>> irinotecan etc. No radiation though.
> >>>
> >>> As of my last scan, tumors where held in check - no growth, some
> >>> shrinkage. So my onc took my off treatment to give me a break - 10
> >>> weeks perhaps.
> >>>
> >>> My question is this: If my next scan shows growth, will it be of any
> >>> use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
> >>> has "shot its load" is it no longer effective? I'm wondering if, after
> >>> 2 years away from a particular regimen, the body/tumors have changed
> >>> such that the first regimen can be helpful again.
> >>>
> >>> Thanks
> >>
> >>It's likely to be less effective if the tumour has seen it before.
> >>The real question is what are you hoping treatment can achieve if you have
> >>no symptoms
> >>
> >
> >
> > Thanks. I suspected that after treatments, tumors eventually "get
> > smart"and are no longer affected by the chemo. I was hoping though
> > that they "forget" after a while and previous treatments would be
> > affective again. I'm hoping of course for life extension. The symptoms
> > thusfar are only visible on scans and that any treatments whether old
> > or new will retart tumor growth.
> >
>
> There is unfortunately very little evidence that treatment in your
> circumstances will produce any survival extension. You may suffer
> side-effects for no benefit.
>
> > I appreciate your presence in this group and the more technical info
> > you give us. Your time must be at a premium, so thanks from all of us.

This newsgroup needs an affordable book.
The breast cancer newsgroup often recommends one.
The prostate cancer newsgroup often recommend 1- 5 books.
Other support newsgroups often recommend 1 -3 books.
This newsgroup (and the world) needs one good book explaining...
J

After Cancer Treatment: Heal Faster, Better, Stronger (A Johns Hopkins Press
Health Book) (Paperback)
by Julie K. Silver

Understanding Cancer: A Patient's Guide to Diagnosis, Prognosis, and
Treatment (Paperback)
by C. Norman Coleman, Edward C. Halperin


Diagnosis: Cancer: Your Guide to the First Months of Healthy Survivorship,
Expanded and Revised Edition (Paperback)
by Wendy Schlessel Harpham


Cancer: 50 Essential Things to Do: Revised and Updated Edition (Paperback)
by Greg Anderson


The Chemotherapy & Radiation Therapy Survival Guide (Chemotherapy and
Radiation Therapy Survivor's Guide) (Paperback)
by Judith McKay, Nancee Hirano


"J" <ercent@anon.inv> wrote in message
news:454B955A.1A97180F@execulink.com...
> Steph wrote:
>
>> "46erjoe" <somebody@spamless.net> wrote in message
>> > On Wed, 01 Nov 2006 15:10:09 GMT, "Steph" <steph@vancouvers.island>
>> > wrotF:
>> >
>> >>
>> >>"46erjoe" <somebody@spamless.net> wrote in message
>> >>> This is a question that I'm sure sure I've seen answered here or
>> >>> anywhere else on the web. It has to do with resumption of treatment
>> >>> after a long period away from it.
>> >>>
>> >>> I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
>> >>> irinotecan etc. No radiation though.
>> >>>
>> >>> As of my last scan, tumors where held in check - no growth, some
>> >>> shrinkage. So my onc took my off treatment to give me a break - 10
>> >>> weeks perhaps.
>> >>>
>> >>> My question is this: If my next scan shows growth, will it be of any
>> >>> use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
>> >>> has "shot its load" is it no longer effective? I'm wondering if,
>> >>> after
>> >>> 2 years away from a particular regimen, the body/tumors have changed
>> >>> such that the first regimen can be helpful again.
>> >>>
>> >>> Thanks
>> >>
>> >>It's likely to be less effective if the tumour has seen it before.
>> >>The real question is what are you hoping treatment can achieve if you
>> >>have
>> >>no symptoms
>> >>
>> >
>> >
>> > Thanks. I suspected that after treatments, tumors eventually "get
>> > smart"and are no longer affected by the chemo. I was hoping though
>> > that they "forget" after a while and previous treatments would be
>> > affective again. I'm hoping of course for life extension. The symptoms
>> > thusfar are only visible on scans and that any treatments whether old
>> > or new will retart tumor growth.
>> >
>>
>> There is unfortunately very little evidence that treatment in your
>> circumstances will produce any survival extension. You may suffer
>> side-effects for no benefit.
>>
>> > I appreciate your presence in this group and the more technical info
>> > you give us. Your time must be at a premium, so thanks from all of us.
>
> This newsgroup needs an affordable book.
> The breast cancer newsgroup often recommends one.
> The prostate cancer newsgroup often recommend 1- 5 books.
> Other support newsgroups often recommend 1 -3 books.
> This newsgroup (and the world) needs one good book explaining...
> J
>

"J" <ercent@anon.inv> wrote in message
news:454B955A.1A97180F@execulink.com...
> Steph wrote:
>
>> "46erjoe" <somebody@spamless.net> wrote in message
>> > On Wed, 01 Nov 2006 15:10:09 GMT, "Steph" <steph@vancouvers.island>
>> > wrotF:
>> >
>> >>
>> >>"46erjoe" <somebody@spamless.net> wrote in message
>> >>> This is a question that I'm sure sure I've seen answered here or
>> >>> anywhere else on the web. It has to do with resumption of treatment
>> >>> after a long period away from it.
>> >>>
>> >>> I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
>> >>> irinotecan etc. No radiation though.
>> >>>
>> >>> As of my last scan, tumors where held in check - no growth, some
>> >>> shrinkage. So my onc took my off treatment to give me a break - 10
>> >>> weeks perhaps.
>> >>>
>> >>> My question is this: If my next scan shows growth, will it be of any
>> >>> use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
>> >>> has "shot its load" is it no longer effective? I'm wondering if,
>> >>> after
>> >>> 2 years away from a particular regimen, the body/tumors have changed
>> >>> such that the first regimen can be helpful again.
>> >>>
>> >>> Thanks
>> >>
>> >>It's likely to be less effective if the tumour has seen it before.
>> >>The real question is what are you hoping treatment can achieve if you
>> >>have
>> >>no symptoms
>> >>
>> >
>> >
>> > Thanks. I suspected that after treatments, tumors eventually "get
>> > smart"and are no longer affected by the chemo. I was hoping though
>> > that they "forget" after a while and previous treatments would be
>> > affective again. I'm hoping of course for life extension. The symptoms
>> > thusfar are only visible on scans and that any treatments whether old
>> > or new will retart tumor growth.
>> >
>>
>> There is unfortunately very little evidence that treatment in your
>> circumstances will produce any survival extension. You may suffer
>> side-effects for no benefit.
>>
>> > I appreciate your presence in this group and the more technical info
>> > you give us. Your time must be at a premium, so thanks from all of us.
>
> This newsgroup needs an affordable book.
> The breast cancer newsgroup often recommends one.
> The prostate cancer newsgroup often recommend 1- 5 books.
> Other support newsgroups often recommend 1 -3 books.
> This newsgroup (and the world) needs one good book explaining...
> J
>

It's still on the way.............with a little help from my friends

alex wrote:

> After Cancer Treatment: Heal Faster, Better, Stronger (A Johns Hopkins Press
> Health Book) (Paperback)
> by Julie K. Silver
>
> Understanding Cancer: A Patient's Guide to Diagnosis, Prognosis, and
> Treatment (Paperback) **********
> by C. Norman Coleman, Edward C. Halperin
>
> Diagnosis: Cancer: Your Guide to the First Months of Healthy Survivorship,
> Expanded and Revised Edition (Paperback)
> by Wendy Schlessel Harpham
>
> Cancer: 50 Essential Things to Do: Revised and Updated Edition (Paperback)
> by Greg Anderson
>
> The Chemotherapy & Radiation Therapy Survival Guide (Chemotherapy and
> Radiation Therapy Survivor's Guide) (Paperback)
> by Judith McKay, Nancee Hirano

Some might be helpful to some and there's more here
http://www.cancersupporters.com/asc/misc.html

but I think the ultimate book about cancer will come from Steph.
J
********not available at our librairies, not the 1999 version, nor the 2nd
Edition (2006) so I can't check it out..
J

Steph wrote:

> "J" <ercent@anon.inv> wrote in message
>
> > Steph wrote:
> >
> >> "46erjoe" <somebody@spamless.net> wrote in message
> >> > On Wed, 01 Nov 2006 15:10:09 GMT, "Steph" <steph@vancouvers.island>
> >>
> >> There is unfortunately very little evidence that treatment in your
> >> circumstances will produce any survival extension. You may suffer
> >> side-effects for no benefit.
> >>
> >> > I appreciate your presence in this group and the more technical info
> >> > you give us. Your time must be at a premium, so thanks from all of us.
> >
> > This newsgroup needs an affordable book.
> > The breast cancer newsgroup often recommends one.
> > The prostate cancer newsgroup often recommend 1- 5 books.
> > Other support newsgroups often recommend 1 -3 books.
> > This newsgroup (and the world) needs one good book explaining...
> > J
> >
>
> It's still on the way.............with a little help from my friends

Thanks Steph,
I look forward to reading it.
J

You are writing a book? I don't know when you find time, but I look
forward to reading it.

Is it peppered with pithy comments?

Fig

On Nov 4, 1:03 am, "Steph" <s...@vancouvers.island> wrote:
> "J" <erc...@anon.inv> wrote in messagenews:454B955A.1A97180F@execulink.com...
>
>
>
>
>
> > Steph wrote:
>
> >> "46erjoe" <someb...@spamless.net> wrote in message
> >> > On Wed, 01 Nov 2006 15:10:09 GMT, "Steph" <s...@vancouvers.island>
> >> > wrotF:
>
> >> >>"46erjoe" <someb...@spamless.net> wrote in message
> >> >>> This is a question that I'm sure sure I've seen answered here or
> >> >>> anywhere else on the web. It has to do with resumption of treatment
> >> >>> after a long period away from it.
>
> >> >>> I've been through the Folfox 5FU Avastin Oxaliplatin erbitux
> >> >>> irinotecan etc. No radiation though.
>
> >> >>> As of my last scan, tumors where held in check - no growth, some
> >> >>> shrinkage. So my onc took my off treatment to give me a break - 10
> >> >>> weeks perhaps.
>
> >> >>> My question is this: If my next scan shows growth, will it be of any
> >> >>> use to go back on EARLIER treatments, eg 5FU? Or, once a treatment
> >> >>> has "shot its load" is it no longer effective? I'm wondering if,
> >> >>> after
> >> >>> 2 years away from a particular regimen, the body/tumors have changed
> >> >>> such that the first regimen can be helpful again.
>
> >> >>> Thanks
>
> >> >>It's likely to be less effective if the tumour has seen it before.
> >> >>The real question is what are you hoping treatment can achieve if you
> >> >>have
> >> >>no symptoms
>
> >> > Thanks. I suspected that after treatments, tumors eventually "get
> >> > smart"and are no longer affected by the chemo. I was hoping though
> >> > that they "forget" after a while and previous treatments would be
> >> > affective again. I'm hoping of course for life extension. The symptoms
> >> > thusfar are only visible on scans and that any treatments whether old
> >> > or new will retart tumor growth.
>
> >> There is unfortunately very little evidence that treatment in your
> >> circumstances will produce any survival extension. You may suffer
> >> side-effects for no benefit.
>
> >> > I appreciate your presence in this group and the more technical info
> >> > you give us. Your time must be at a premium, so thanks from all of us.
>
> > This newsgroup needs an affordable book.
> > The breast cancer newsgroup often recommends one.
> > The prostate cancer newsgroup often recommend 1- 5 books.
> > Other support newsgroups often recommend 1 -3 books.
> > This newsgroup (and the world) needs one good book explaining...
> > JIt's still on the way.............with a little help from my friends- Hide quoted text -- Show quoted text -

"Figgertoes" <figtoes@yahoo.com> wrote in message
news:1162648626.278382.236710@b28g2000cwb.googlegr oups.com...
> You are writing a book? I don't know when you find time, but I look
> forward to reading it.
>
> Is it peppered with pithy comments?
>
> Fig

That wouldn't be like me, Fig...............