Re: Catalytic Iron In Asbestos

On Sep 12, 10:20*am, anonym...@nowhere.you.know wrote: snip <<

Anonymous .. and .. the psychotic jwooton .. appear together ..

"Phytic acid blocks asbestos"


That would be my free bisphosphonate again.
http://tinyurl.com/2au4yx


P53 mediates amosite asbestos-induced alveolar epithelial cell
mitochondria-regulated apoptosis.
Apr 2006
Vijayalakshmi Panduri,Sailesh Surapureddi,Saul Soberanes,Sigmund A
Weitzman,Navdeep Chandel,David W Kamp
Asbestos causes pulmonary toxicity in part by generating reactive
oxygen species that cause DNA damage.
We previously showed that the mitochondria-regulated (intrinsic)
death
pathway mediates alveolar epithelial cell (AEC) DNA damage and
apoptosis.
Because p53 regulates the DNA damage response in part by inducing
intrinsic cell death, we determined whether p53-dependent
transcriptional activity mediates asbestos-induced AEC mitochondrial
dysfunction and apoptosis.
We show that inhibitors of p53-dependent transcriptional activation
(pifithrin and type 16-E6 protein) block asbestos-induced AEC
mitochondrial membrane potential change (DeltaPsim), caspase 9
activation, and apoptosis.
We demonstrate that asbestos activates p53 promoter activity, mRNA
levels, protein expression, and Bax and p53 mitochondrial
translocation.
Further, pifithrin, E6, phytic acid, or rho(0)-A549 cells (cells
incapable of mitochondrial reactive oxygen species production) block
asbestos-induced p53 activation.
Finally, we show that asbestos augments p53 expression in cells at
the
bronchoalveolar duct junctions of rat lungs and that phytic acid
prevents this.
These data suggest that p53-dependent transcription pathways mediate
asbestos-induced AEC mitochondria-regulated apoptosis.
This suggests an important interactive effect between p53 and the
mitochondria in the pathogenesis of asbestos-induced pulmonary
toxicity that may have broader implications for our understanding of
pulmonary fibrosis and lung cancer.


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/634q5a


Man Is A Herbivore!
http://tinyurl.com/4rq595


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

We note you are unable/unwilling to answerthe below, consider again.

u'll never change his belief system. Many people have tried for over

ars.
y don't you quit replying to him _unless_ he posts something very
ngerous, which he does from time to time.
r trim out the support newsgroup - most other support newsgroups would
preciate it as well) But that's more work.
u, he, spammers, lawyers looking for mesothelioma patients and others
e
king a mess of alt.support.cancer.
ank you for your kind consideration of my request.

On Sep 12, 2:26*pm, anonym...@nowhere.you.know wrote: snip <<

Why don't you just step .. up ..

You don't have the cojones .. ?

You figure .. anonymous .. posting are the .. thing to .. dooooo ..
there .. pussy .. ?

Is that how you figure .. it .. works .. ?

Is it .. ?

Explain how you figure .. anonymous .. posts are the way to go .. ?

Just so I see the sense of it ..

Maybe others .. can see the sense to it ..

But since noone is reading my posts .. and it IS .. just you and
me ..

Step .. up ..

You have a question .. do ya .. ?

What kind of question can you pull out of your ass ..

None that I've given ya ..

Pull .. a .. question .. out of your .. ass ..

Heh .. heh ..


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/634q5a


Man Is A Herbivore!
http://tinyurl.com/4rq595


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk


> We note you are unable/unwilling to answerthe below, consider again.
>
> u'll never change his belief system. *Many people have tried for over
>
> ars.
> y don't you quit replying to him _unless_ he posts something very
> ngerous, which he does from time to time.
> r trim out the support newsgroup - most other support newsgroups would
> preciate it as well) But that's more work.
> u, he, spammers, lawyers looking for mesothelioma patients and others
> e
> king a mess of alt.support.cancer.
> ank you for your kind consideration of my request.