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The difference between T1 and T2
  1. #1
    GysdeJongh Guest

    Default The difference between T1 and T2


    <http://www.nature.com/nature/journal/v485/n7398_supp/full/485S10a.html>

    <http://www.nature.com/nature/journal/v485/n7398_supp/pdf/485S10a.pdf>

    Type 1 and type 2 diabetes have long been viewed as two diseases, the first
    auto-immune with a large genetic component, the second metabolic, linked to
    obesity and a sedentary lifestyle. "These are two very different disorders,"
    says C. Ronald Kahn, a senior investigator at Joslin Diabetes Center and
    professor of medicine at Harvard Medical School in Boston, Massachusetts.
    "They lead to similar metabolic problems and similar long-term
    complications, but they have two very different pathogenic routes."
    Researchers, however, are showing that each type has more in common with the
    other than once believed: both involve a faulty immune system and share some
    mechanisms that ultimately kill the insulin-producing beta cells in the
    pancreatic islets. Yet in neither type 1 diabetes (T1D) nor type 2 diabetes
    (T2D) does genetics or behaviour fully explain why some people get the
    disease and others don't. Recent findings show that despite some common risk
    factors, the two are indeed separate conditions. In addition to the many
    genetic factors involved, scientists have implicated epigenetic and
    environmental influence in each type of diabetes. Researchers continue to
    search for certain causes in an effort to prevent both.

    Nature. 2012 May 17;485(7398):S10-11.
    Pathology: Cause and effect.
    Jonietz E.
    PMID: 22616098


  2. #2
    Chris Hogg Guest

    Default Re: The difference between T1 and T2

    1

    Sorry! Feeling frivolous tonight :-)

    --

    Chris

    T2 DX'd 2002, D&E, HbA1c 5.9, BMI 21
    Lipids:Tot 5.2 HDL 1.6 LDL 3.2 Tri 0.8

  3. #3
    GysdeJongh Guest

    Default Re: The difference between T1 and T2

    Chris Hogg wrote:
    > 1
    >
    > Sorry! Feeling frivolous tonight :-)




  4. #4
    Ozlover Guest

    Default Re: The difference between T1 and T2

    Chris Hogg <[email protected]> wrote:
    > 1
    >
    > Sorry! Feeling frivolous tonight :-)


    I think you meant "-1"! :-)

    And in my case: T2 is newer and bigger than T1!



    Our (slide-on) camper is called "T2". The "T" stands for Tardis,
    because it is bigger inside than it looks on the outside. Our Aussie
    relly who built it, first built his own camper, which is of course
    called "T1". So when I call him on the radio, it's "T2 calling T1,
    over". It's probably hard to believe, but, until this thread, I never
    associated it with diabetes.

    --
    Frank Slootweg

  5. #5
    W. Baker Guest

    Default Re: The difference between T1 and T2

    Ozlover <[email protected]> wrote:
    : Chris Hogg <[email protected]> wrote:
    : > 1
    : >
    : > Sorry! Feeling frivolous tonight :-)

    : I think you meant "-1"! :-)

    : And in my case: T2 is newer and bigger than T1!

    : ^L

    : Our (slide-on) camper is called "T2". The "T" stands for Tardis,
    : because it is bigger inside than it looks on the outside. Our Aussie
    : relly who built it, first built his own camper, which is of course
    : called "T1". So when I call him on the radio, it's "T2 calling T1,
    : over". It's probably hard to believe, but, until this thread, I never
    : associated it with diabetes.

    : --
    : Frank Slootweg

    Are there anyof those Tardis phone boothes left in Great Britain?

    Wendy

  6. #6
    Chris Hogg Guest

    Default Re: The difference between T1 and T2

    On 22 Jul 2012 19:43:03 GMT, Ozlover <[email protected]> wrote:

    >Chris Hogg <[email protected]> wrote:
    >> 1
    >>
    >> Sorry! Feeling frivolous tonight :-)

    >
    > I think you meant "-1"! :-)
    >

    <chuckle>

    It could also be T (or -T) !

    --

    Chris

    T2 DX'd 2002, D&E, HbA1c 5.9, BMI 21
    Lipids:Tot 5.2 HDL 1.6 LDL 3.2 Tri 0.8

  7. #7
    Chris Malcolm Guest

    Default Re: The difference between T1 and T2

    W. Baker <[email protected]> wrote:
    > Ozlover <[email protected]> wrote:
    > : Chris Hogg <[email protected]> wrote:


    > : Our (slide-on) camper is called "T2". The "T" stands for Tardis,
    > : because it is bigger inside than it looks on the outside. Our Aussie
    > : relly who built it, first built his own camper, which is of course
    > : called "T1". So when I call him on the radio, it's "T2 calling T1,
    > : over". It's probably hard to believe, but, until this thread, I never
    > : associated it with diabetes.


    > : --
    > : Frank Slootweg


    > Are there anyof those Tardis phone boothes left in Great Britain?


    Lots. What's more, since the police use them much less than they used
    to, some are for sale, and some are for rent. A popular use for them
    is as street coffee stalls.

    --
    Chris Malcolm

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