Itching skin,with temp change

My T2 spouse (on oral meds and Novalog) has been experiencing really
infuriating itching when he goes from a warm environment to a cooler
environment. This seems to be mostly on his arms, legs and any other
exposed area. He says it is getting so bad, he almost can't stand it! Is
this a diabetic phenomenon, have any of you gurus experienced this?

TIA for any input. He says he will be telling his Dr about it when he
sees him at the next visit.

Gillian, in Florida.

x-no-archive: yes

Gill Murray wrote:
> My T2 spouse (on oral meds and Novalog) has been experiencing really
> infuriating itching when he goes from a warm environment to a cooler
> environment. This seems to be mostly on his arms, legs and any other
> exposed area. He says it is getting so bad, he almost can't stand it! Is
> this a diabetic phenomenon, have any of you gurus experienced this?
>
> TIA for any input. He says he will be telling his Dr about it when he
> sees him at the next visit.

A lot of us experience severe itchy skin with higher bgs, but I can't
say I've noticed it at other times. The exception would be before I was
diagnosed and treated with high dose doxycycline for tick borne
diseases; I was ready to kill myself over full body nighttime itches,
but they've been gone for years since the first dose of doxy.

I bought some Sarna anti itch lotion for sensitive skin for my FIL just
before he died and it stopped severe itching very effectively. Might be
a stopgap for your husband.

Susan

On Apr 16, 12:05 pm, Gill Murray <gillmurr...@nowhere.net> wrote:
> My T2 spouse (on oral meds and Novalog) has been experiencing really
> infuriating itching when he goes from a warm environment to a cooler
> environment. This seems to be mostly on his arms, legs and any other
> exposed area. He says it is getting so bad, he almost can't stand it! Is
> this a diabetic phenomenon, have any of you gurus experienced this?
>
> TIA for any input. He says he will be telling his Dr about it when he
> sees him at the next visit.

Is there any rash? A couple of times over the years I've had some kind
of allergy - maybe a food allergy - which gave me lots of itchy red
bumps all over me. My doc recommended OTC antihistamines, which took
care of the problem. I tried to pin him down on if my diabetes
could've been related to the rash, but he refused to make any
connection. I haven't had this problem in 15 years.

There is such a phenomenon as "insulin allergy" but it's much much
rarer today than when animal insulins were being used. It can cause
itching around the injection site in some forms, but I haven't heard
of it causing itching all over. If the itching is only at/near
injection sites, this is definitely something to bring up with the
doc, preferably before the next visit.

Tim.

In article <Q8NUh.996$Qp.884@trnddc07>, Gill Murray
<gillmurray1@nowhere.net> wrote:

> My T2 spouse (on oral meds and Novalog) has been experiencing really
> infuriating itching when he goes from a warm environment to a cooler
> environment.

http://en.wikipedia.org/wiki/Chronic_cold_urticaria

is what I have. Had it most of my life.

In my case:

- may have been aggravated by Lipitor which I am no longer taking due
to other side effects.

- comes and goes over months.

- may have been aggravated by recent onset of T2 diabetes and the
glyburide I am now taking, which has urticaria listed among its side
effects, or just may be idiopathic.

YMMV.

--
To reply, substitute .com for .invalid in address, i.e., john.101a (at)
*yahoo.com

On Apr 16, 2:10 pm, John101 <john.1...@yahoo.invalid> wrote:
> In article <Q8NUh.996$Qp.884@trnddc07>, Gill Murray
>
> <gillmurr...@nowhere.net> wrote:
> > My T2 spouse (on oral meds and Novalog) has been experiencing really
> > infuriating itching when he goes from a warm environment to a cooler
> > environment.
>
> http://en.wikipedia.org/wiki/Chronic_cold_urticaria
>
> is what I have. Had it most of my life.

Fascinating. I never associated what I experienced with cold
temperatures and my condition wasn't chronic but just occasional, but
if I google urticaria I see that it is sometimes associated with
autoimmune conditions including hypothyroidism and T1 diabetes (which
I have both of). And according to the Wikipedia, the age range where
it's most common (18-25) is exactly the age range that I experienced
it at!

Thanks for the word and the link! I can't say it explains everything
to me but it makes feel like the when I got the hives in my college
years, that it might not have just been a food allergy!

Tim.

shoppa@trailing-edge.com wrote:
> On Apr 16, 12:05 pm, Gill Murray <gillmurr...@nowhere.net> wrote:
>
>>My T2 spouse (on oral meds and Novalog) has been experiencing really
>>infuriating itching when he goes from a warm environment to a cooler
>>environment. This seems to be mostly on his arms, legs and any other
>>exposed area. He says it is getting so bad, he almost can't stand it! Is
>>this a diabetic phenomenon, have any of you gurus experienced this?
>>
>>TIA for any input. He says he will be telling his Dr about it when he
>>sees him at the next visit.
>
>
> Is there any rash? A couple of times over the years I've had some kind
> of allergy - maybe a food allergy - which gave me lots of itchy red
> bumps all over me. My doc recommended OTC antihistamines, which took
> care of the problem. I tried to pin him down on if my diabetes
> could've been related to the rash, but he refused to make any
> connection. I haven't had this problem in 15 years.
>
> There is such a phenomenon as "insulin allergy" but it's much much
> rarer today than when animal insulins were being used. It can cause
> itching around the injection site in some forms, but I haven't heard
> of it causing itching all over. If the itching is only at/near
> injection sites, this is definitely something to bring up with the
> doc, preferably before the next visit.
>
> Tim.
>
No rash, Tim, and it started years before he was a diagnosed diabetic,
or went on insulin!!

Appreciate the info, though. Getting older isn't always fun, is it?

Gillian

Susan wrote:
> x-no-archive: yes
>
> Gill Murray wrote:
>
>> My T2 spouse (on oral meds and Novalog) has been experiencing really
>> infuriating itching when he goes from a warm environment to a cooler
>> environment. This seems to be mostly on his arms, legs and any other
>> exposed area. He says it is getting so bad, he almost can't stand it!
>> Is this a diabetic phenomenon, have any of you gurus experienced this?
>>
>> TIA for any input. He says he will be telling his Dr about it when he
>> sees him at the next visit.
>
>
> A lot of us experience severe itchy skin with higher bgs, but I can't
> say I've noticed it at other times. The exception would be before I was
> diagnosed and treated with high dose doxycycline for tick borne
> diseases; I was ready to kill myself over full body nighttime itches,
> but they've been gone for years since the first dose of doxy.
>
> I bought some Sarna anti itch lotion for sensitive skin for my FIL just
> before he died and it stopped severe itching very effectively. Might be
> a stopgap for your husband.
>
> Susan
Thanks Susan for the input.

After I forwarded your email to my DH, he reminded me that he first
started itching about 15 years ago, way before he was diagnosed with
diabetes, or hyperlipidemia. He would get out of the swimming pool and
itch. I really don't remember it, so I guess it wasn't that major. Mow,
it is really bad.

He has your post to add to his input to the doc this month

Gillian

John101 wrote:
> In article <Q8NUh.996$Qp.884@trnddc07>, Gill Murray
> <gillmurray1@nowhere.net> wrote:
>
>
>>My T2 spouse (on oral meds and Novalog) has been experiencing really
>>infuriating itching when he goes from a warm environment to a cooler
>>environment.
>
>
> http://en.wikipedia.org/wiki/Chronic_cold_urticaria
>
> is what I have. Had it most of my life.
>
> In my case:
>
> - may have been aggravated by Lipitor which I am no longer taking due
> to other side effects.
>
> - comes and goes over months.
>
> - may have been aggravated by recent onset of T2 diabetes and the
> glyburide I am now taking, which has urticaria listed among its side
> effects, or just may be idiopathic.
>
> YMMV.
>
Now that was a good idea; he has been on Lipitor, metformin and
glyburide for several years now. He tells me this started in a mild
manner many years before he took any meds. My thought is that the meds,
plus age may be attributing to the problem. He has "said" he will talk
to his doc, but who knows??

Thanks for the great ideas.

Gillian

> he has been on Lipitor,

My urticaria a year ago was the worst I had ever had. (Until I read
that Wikipedia article in preparing my previous post I didn't realize
how severe it can get, wow)

Three days after I stopped taking Lipitor because of other side effects
(I googled one morning, found Lipitor was capable of causing the
problem I was having, stopped taking Lipitor that morning and my
problem went away),

What surprised me was within 3 days my urticaria problem also vanished
completely.

I then looked up Lipitor side effects and found the urticaria was a
known side effect.

(Lipitor is a bit scary, I have never seen such a long list of side
effects for a drug.

Since I have been restricting my carbs for obvious reasons as a T2, my
lipids have snapped back to being absolutely perfect so nobody is
suggesting I take Lipitor again)

A year later the urticaria has returned but is not as severe.

YMMV.

Cheers,

Darrell

--
To reply, substitute .com for .invalid in address, i.e., john.101a (at)
*yahoo.com

> >> > >> Is this a diabetic phenomenon, have any of you gurus experienced
this?


I should have known something was wrong b4 my diagnosis. I itched,
sometimes until I bled on my hands. I would get rashes (kept telling myself
it was the soap). Little bumps would appear, like with a little fluid in
them. It might be a little place with bumps, then it would start spreading
and appear not only in-between the fingers, but on my hands. I found a
prescription cream that works really well for me when it gets bad, however,
since my BS is down, the itching it less, and the problems are not as
frequent. As far as body itching, since I was diagnosed, I have been using
lotion daily for general dry itchy skin...the rash bumps I have to keep dry
or they itch worse.
Kris

On Thu, 19 Apr 2007 23:20:09 -0500, "Cougar"
<cougar_rocklightening@yahoo.com> wrote:

>> >> > >> Is this a diabetic phenomenon, have any of you gurus experienced
>this?
>
>
>I should have known something was wrong b4 my diagnosis. I itched,
>sometimes until I bled on my hands. I would get rashes (kept telling myself
>it was the soap). Little bumps would appear, like with a little fluid in
>them. It might be a little place with bumps, then it would start spreading
>and appear not only in-between the fingers, but on my hands. I found a
>prescription cream that works really well for me when it gets bad, however,
>since my BS is down, the itching it less, and the problems are not as
>frequent. As far as body itching, since I was diagnosed, I have been using
>lotion daily for general dry itchy skin...the rash bumps I have to keep dry
>or they itch worse.
>Kris
>
I had a lot of itching, more like bites. Docs looked
at and duh. As time went by it becme worse.

Finally it became acute and I sought an answer.
All kinds of bull. One doc started to ask me
"depression" questions. I whipped my wheel
chairr around and said "we are not going there"
"I have al the symton od a systemic parasite infeecdtion".

A week later I was diagnosd with a wide spread hook worm
nfection. Proper drugs are alleviating the problem but at
time I see it as never ending.

A few pills could have stopped it permanently at one time.

Many GP's seem to be unqualified to handle these problems

I heard that old "Diabetics seem to have problems like this"
HIde rthe sympoms with cortisone type drugs.

A good soource of these problem is health care
facilities like a lot of diabetic problems like fungal
and yeast..

There some good drugs but it is not easy.
Cortisone is not ne of them.

When I have the final solutioin, I wiull post it.

Most itchng has a cause.,

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>>On Apr 16, 9:05 am, Gill Murray <gillmurr...@nowhere.net> wrote:
My T2 spouse (on oral meds and Novalog) has been experiencing really
infuriating itching when he goes from a warm environment to a cooler
environment. This seems to be mostly on his arms, legs and any other
exposed area. He says it is getting so bad, he almost can't stand it!
Is
this a diabetic phenomenon, have any of you gurus experienced this?<<

This is a very common manifestation of increased red blood cell
producton / viscosity / polycythemia / increased
red blood cell count . the blood cannot properly .. flow .. because
of the **thickness** OF the blood.
Secondary polycythemia / increased
red blood cell count has been shown to be associated with diabetes.

http://cat.inist.fr/?aModele=afficheN&cpsidt=14148834

<<snip>>
Increased
red blood cell count could be considered as a new aspect of the
insulin
resistance syndrome that could contribute to the increased risk of
developing cardiovascular problems.
<<snip>>

PMID: 11692171 [PubMed - indexed for MEDLINE]


<<snip>>
episodes of facial flushing, warmth of the palms and soles of feet,
throbbing headache, fullness in the head, dizziness, lethargy,
prickling sensation, pruritus / itch and arthralgia.
<<snip>>

Heavy smoking and liver.
El-Zayadi AR
World J Gastroenterol. 2006 Oct 14; 12(38): 6098-101


Smoking causes a variety of adverse effects on organs that have no
direct contact with the smoke itself such as the liver. It induces
three major adverse effects on the liver: direct or indirect toxic
effects, immunological effects and oncogenic effects. Smoking yields
chemical substances with cytotoxic potential which increase
necroinflammation and fibrosis. In addition, smoking increases the
production of pro-inflammatory cytokines (IL-1, IL-6 and TNF- alpha)
that would be involved in liver cell injury. It contributes to the
development of secondary polycythemia and in turn to increased red
cell
mass and turnover which might be a contributing factor to secondary
iron overload disease promoting oxidative stress of hepatocytes.
Increased red cell mass and turnover are associated with increased
purine catabolism which promotes excessive production of uric acid.
Smoking affects both cell-mediated and humoral immune responses by
blocking lymphocyte proliferation and inducing apoptosis of
lymphocytes. Smoking also increases serum and hepatic iron which
induce
oxidative stress and lipid peroxidation that lead to activation of
stellate cells and development of fibrosis. Smoking yields chemicals
with oncogenic potential that increase the risk of hepatocellular
carcinoma (HCC) in patients with viral hepatitis and are independent
of
viral infection as well. Tobacco smoking has been associated with
supression of p53 (tumour suppressor gene). In addition, smoking
causes
suppression of T-cell responses and is associated with decreased
surveillance for tumour cells. Moreover, it has been reported that
heavy smoking affects the sustained virological response to
interferon
(IFN) therapy in hepatitis C patients which can be improved by
repeated
phlebotomy. Smoker's syndrome is a clinico-pathological condition
where
patients complain of episodes of facial flushing, warmth of the palms
and soles of feet, throbbing headache, fullness in the head,
dizziness,
lethargy, prickling sensation, pruritus and arthralgia.


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