Max Metformin Dosage

What's the maximum dosage per day of Metformin
which doctors prescribe?

Does it differ between Metformin Regular & Metformin
XR?

lll wrote:
> What's the maximum dosage per day of Metformin
> which doctors prescribe?

Depends on the formulation.

> Does it differ between Metformin Regular & Metformin
> XR?

Yes.

2000 mg is max for the extended release (XR aka ER)

2550 mg is max for the regular

These maximum numbers are for healthy kidneys and close monitoring of
serum creatinine.

May GOD continue to heal our hearts with HIS living water so that we
can love others a little bit more, dear neighbor whom I love
unconditionally.

Prayerfully in Christ's amazing love,

Andrew <><
--
Andrew B. Chung
Cardiologist, Atlanta, Georgia, USA
http://HeartMDPhD.com/HolySpirit

As for knowing who are the very elect, these you will know by the
unconditional love they have for everyone including their enemies
(Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17).
http://HeartMDPhD.com/Love

lll wrote:
> What's the maximum dosage per day of Metformin
> which doctors prescribe?
>
> Does it differ between Metformin Regular & Metformin
> XR?

This is the generally accepted rule:
Metformin HCI

The usual starting dose is one 500-milligram tablet twice a day,
taken with morning and evening meals. Your doctor may increase
your daily dose by 500 milligrams at weekly intervals, based on
your response up to a total of 2,000 milligrams.

An alternative starting dose is one 850-milligram tablet a day,
taken with the morning meal. Your doctor may increase this by
850 milligrams at 14-day intervals, to a maximum of 2,550
milligrams a day.

The usual maintenance dose ranges from 1,500 to 2,550 milligrams
daily. If you take more than 2,000 milligrams a day, your doctor
may recommend that metformin be divided into three doses, taken
with each meal.

Metformin XR

The usual starting dose is one 500-milligram tablet once daily
with the evening meal. Your doctor may increase your dose by 500
milligrams at weekly intervals, up to a maximum dosage of 2,000
milligrams a day. If a single 2,000-milligram dose fails to
control your blood sugar, you may be asked to take
1,000-milligram doses twice a day. If you need more than 2,000
milligrams a day, the doctor will switch you to regular
metformin.



C

Chrome wrote:
> lll wrote:
>> What's the maximum dosage per day of Metformin
>> which doctors prescribe?
>>
>> Does it differ between Metformin Regular & Metformin
>> XR?
>
> This is the generally accepted rule:
> Metformin HCI
>
> The usual starting dose is one 500-milligram tablet twice a day,
> taken with morning and evening meals. Your doctor may increase
> your daily dose by 500 milligrams at weekly intervals, based on
> your response up to a total of 2,000 milligrams.
>
> An alternative starting dose is one 850-milligram tablet a day,
> taken with the morning meal. Your doctor may increase this by
> 850 milligrams at 14-day intervals, to a maximum of 2,550
> milligrams a day.
>
> The usual maintenance dose ranges from 1,500 to 2,550 milligrams
> daily. If you take more than 2,000 milligrams a day, your doctor
> may recommend that metformin be divided into three doses, taken
> with each meal.
>
> Metformin XR
>
> The usual starting dose is one 500-milligram tablet once daily
> with the evening meal. Your doctor may increase your dose by 500
> milligrams at weekly intervals, up to a maximum dosage of 2,000
> milligrams a day. If a single 2,000-milligram dose fails to
> control your blood sugar, you may be asked to take
> 1,000-milligram doses twice a day. If you need more than 2,000
> milligrams a day, the doctor will switch you to regular
> metformin.

Why different max dosage between Regular & XR?

lll wrote:

> Why different max dosage between Regular & XR?

Pharmacokinetics.

May GOD continue to heal our hearts with HIS living water so that we
can love others a little bit more, dear neighbor whom I love
unconditionally.

Prayerfully in Christ's amazing love,

Andrew <><
--
Andrew B. Chung
Cardiologist, Atlanta, Georgia, USA
http://HeartMDPhD.com/HolySpirit

As for knowing who are the very elect, these you will know by the
unconditional love they have for everyone including their enemies
(Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17).
http://HeartMDPhD.com/Love

"lll" <lll@6url.com> wrote in message
news:4td1q9F13f886U1@mid.individual.net...
> What's the maximum dosage per day of Metformin
> which doctors prescribe?
>
2500 mg.

> Does it differ between Metformin Regular & Metformin
> XR?

Don't think so.

--
See my webpage:
http://mysite.verizon.net/juliebove/index.htm
>
>

Julie Bove wrote:
> "lll" <lll@6url.com> wrote in message
> news:4td1q9F13f886U1@mid.individual.net...
> > What's the maximum dosage per day of Metformin
> > which doctors prescribe?
> >
> 2500 mg.
>
> > Does it differ between Metformin Regular & Metformin
> > XR?
>
> Don't think so.

Actually it does. 2500 mg is excessive for the XR (aka ER)

May GOD continue to heal our hearts with HIS living water so that we
can love others a little more, dear Julie whom I love unconditionally.

Prayerfully in Christ's amazing love,

Andrew <><
--
Andrew B. Chung
Cardiologist, Atlanta, Georgia, USA
http://HeartMDPhD.com/HolySpirit

As for knowing who are the very elect, these you will know by the
unconditional love they have for everyone including their enemies
(Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17).
http://HeartMDPhD.com/Love

x-no-archive: yes

Julie Bove wrote:
> "lll" <lll@6url.com> wrote in message
> news:4td1q9F13f886U1@mid.individual.net...
>
>>What's the maximum dosage per day of Metformin
>>which doctors prescribe?
>>
>
> 2500 mg.

It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S.
Australia, I believe, has a max of 3000.

>
>
>>Does it differ between Metformin Regular & Metformin
>>XR?
>
>
> Don't think so.
>

The maximum daily dose of XR is 2000, by the manufacturer's recommendation.

Susan

Susan wrote:
> x-no-archive: yes
>
> Julie Bove wrote:
>> "lll" <lll@6url.com> wrote in message
>> news:4td1q9F13f886U1@mid.individual.net...
>>
>>> What's the maximum dosage per day of Metformin
>>> which doctors prescribe?
>>>
>>
>> 2500 mg.
>
> It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S.
> Australia, I believe, has a max of 3000.
>
>>
>>
>>> Does it differ between Metformin Regular & Metformin
>>> XR?
>>
>>
>> Don't think so.
>>
>
> The maximum daily dose of XR is 2000, by the manufacturer's
> recommendation.

So why would the max daily dose differ between XR & Regular?

On Sat, 02 Dec 2006 14:03:38 -0500, Susan
<nevermind@nomail.com> wrote:

>
>It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S.
>Australia, I believe, has a max of 3000.

News to me - not that I dispute it, just wasn't aware of
that.

Cheers, Alan, T2, Australia.
d&e, metformin 1000mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraldiabetes.blogspot.com/
http://loraltravel.blogspot.com/
latest: Pompeii, Amalfi, Bari

x-no-archive: yes

lll wrote:

> So why would the max daily dose differ between XR & Regular?
>
>

I dunno, perhaps because it isn't processed/excreted as quickly, a
littler dab'll do ya. :-)

Susan

"Susan" <nevermind@nomail.com> wrote in message
news:4te105F138m5kU1@mid.individual.net...
> x-no-archive: yes
>
> It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S.
> Australia, I believe, has a max of 3000.
>
> Susan


Thats the same as it is here in the UK.

x-no-archive: yes

Alan S wrote:
> On Sat, 02 Dec 2006 14:03:38 -0500, Susan
> <nevermind@nomail.com> wrote:
>
>
>>It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S.
>>Australia, I believe, has a max of 3000.
>
>
> News to me - not that I dispute it, just wasn't aware of
> that.

I think Jan dug that up some time ago when we were discussing it.

Susan

Susan wrote:
> x-no-archive: yes
>
> Alan S wrote:
>> On Sat, 02 Dec 2006 14:03:38 -0500, Susan
>> <nevermind@nomail.com> wrote:
>>
>>
>>>It's actually just a tad higher, at 3 x 850 mg: 2550 in
the U.S.
>>>Australia, I believe, has a max of 3000.
>>
>>
>> News to me - not that I dispute it, just wasn't aware of
>> that.
>
> I think Jan dug that up some time ago when we were
discussing it.

And I can't remember where from either

Ozgirl wrote:
> Susan wrote:
>> x-no-archive: yes
>>
>> Alan S wrote:
>>> On Sat, 02 Dec 2006 14:03:38 -0500, Susan
>>> <nevermind@nomail.com> wrote:
>>>
>>>
>>>>It's actually just a tad higher, at 3 x 850 mg: 2550 in
the U.S.
>>>>Australia, I believe, has a max of 3000.
>>>
>>>
>>> News to me - not that I dispute it, just wasn't aware of
>>> that.
>>
>> I think Jan dug that up some time ago when we were
discussing it.
>
> And I can't remember where from either

Possibly from here:

http://www.npsradar.org.au/site.php?...atestnews.html

On Sun, 3 Dec 2006 10:14:19 +1100, "Ozgirl"
<are_we_there_yet@maccas.com> wrote:

>Ozgirl wrote:
>> Susan wrote:
>>> x-no-archive: yes
>>>
>>> Alan S wrote:
>>>> On Sat, 02 Dec 2006 14:03:38 -0500, Susan
>>>> <nevermind@nomail.com> wrote:
>>>>
>>>>
>>>>>It's actually just a tad higher, at 3 x 850 mg: 2550 in
>the U.S.
>>>>>Australia, I believe, has a max of 3000.
>>>>
>>>>
>>>> News to me - not that I dispute it, just wasn't aware of
>>>> that.
>>>
>>> I think Jan dug that up some time ago when we were
>discussing it.
>>
>> And I can't remember where from either
>
>Possibly from here:
>
>http://www.npsradar.org.au/site.php?...atestnews.html

Thank you. Another new and useful site I hadn't seen before.
Cheers, Alan, T2, Australia.
d&e, metformin 1000mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraldiabetes.blogspot.com/
http://loraltravel.blogspot.com/
latest: Pompeii, Amalfi, Bari

On 12/2/06 3:14 PM, in article 12n4287no9eor21@news.supernews.com, "Ozgirl"
<are_we_there_yet@maccas.com> wrote:

> Ozgirl wrote:
>> Susan wrote:
>>> x-no-archive: yes
>>>
>>> Alan S wrote:
>>>> On Sat, 02 Dec 2006 14:03:38 -0500, Susan
>>>> <nevermind@nomail.com> wrote:
>>>>
>>>>
>>>>> It's actually just a tad higher, at 3 x 850 mg: 2550 in
> the U.S.
>>>>> Australia, I believe, has a max of 3000.
>>>>
>>>>
>>>> News to me - not that I dispute it, just wasn't aware of
>>>> that.
>>>
>>> I think Jan dug that up some time ago when we were
> discussing it.
>>
>> And I can't remember where from either
>
> Possibly from here:
>
> http://www.npsradar.org.au/site.php?...tent/latestnew
> s.html
>
I wonder if there has been a change in their thinking on the maximum dose. I
know that when I was first put on it my doctor and the Diabetes Teaching
Centre said that 2500mg. was the max.

Martha T2 Canada

Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid
control more than anything else at that dose.!! The drug company
responsible ( which one??) really need to start addressing the
pharmacologic aspects of this drug. IMHO it is primarily to deal with
obesity/T2 ! Very few reports suggest the contary.

Larry
Cloudedbrains wrote:
> "Susan" <nevermind@nomail.com> wrote in message
> news:4te105F138m5kU1@mid.individual.net...
> > x-no-archive: yes
> >
> > It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S.
> > Australia, I believe, has a max of 3000.
> >
> > Susan
>
>
> Thats the same as it is here in the UK.

Larry <boelkowj@aol.com> wrote:
: Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid
: control more than anything else at that dose.!! The drug company
: responsible ( which one??) really need to start addressing the
: pharmacologic aspects of this drug. IMHO it is primarily to deal with
: obesity/T2 ! Very few reports suggest the contary.

: Larry

I don't believe tha tMetformin is used primarily as a product fo rdealing
with obesity. It may result in an average weight loss of about 8 lbs!
Not a great deal if one is obese. It deals with the release of glucagon
from the liver, giving you less glucose running around in the bloodstream,
as well as helping with insulin resistance, not pirimarily fo rweight loss
at all. It doesn't tend to cause you to gain weight as inculin or actos
and avandia can.

Wendy

Metformin is used in people likely to have a level of insulin resistance!
Its one of the primary drugs used in t2's IK as its proven to work extremely
well!
I only take 1000mg a day as dont tolerate more even on the slow release!



"W. Baker" <wbaker@panix.com> wrote in message
news:el239n$enc$1@reader2.panix.com...
> Larry <boelkowj@aol.com> wrote:
> : Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid
> : control more than anything else at that dose.!! The drug company
> : responsible ( which one??) really need to start addressing the
> : pharmacologic aspects of this drug. IMHO it is primarily to deal with
> : obesity/T2 ! Very few reports suggest the contary.
>
> : Larry
>
> I don't believe tha tMetformin is used primarily as a product fo rdealing
> with obesity. It may result in an average weight loss of about 8 lbs!
> Not a great deal if one is obese. It deals with the release of glucagon
> from the liver, giving you less glucose running around in the bloodstream,
> as well as helping with insulin resistance, not pirimarily fo rweight loss
> at all. It doesn't tend to cause you to gain weight as inculin or actos
> and avandia can.
>
> Wendy

x-no-archive: yes

Larry wrote:
> Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid
> control more than anything else at that dose.!! The drug company
> responsible ( which one??) really need to start addressing the
> pharmacologic aspects of this drug. IMHO it is primarily to deal with
> obesity/T2 ! Very few reports suggest the contary.

Actually, it's not a weight loss or lipid lowering drug at all.

It improves insulin sensitivity and, to some degree, inhibits glucose
release from the liver.

Susan

In article <crOdnYZENtukPenYnZ2dnUVZ8tWdnZ2d@bt.com>,
"Cloudedbrains" <donna_williamson"@" btopenworld.com> wrote:

> Metformin is used in people likely to have a level of insulin resistance!
> Its one of the primary drugs used in t2's IK as its proven to work extremely
> well!

Uh, did you think Wendy was saying something contradicting that?

Priscilla

> I only take 1000mg a day as dont tolerate more even on the slow release!
>
>
>
> "W. Baker" <wbaker@panix.com> wrote in message
> news:el239n$enc$1@reader2.panix.com...
> > Larry <boelkowj@aol.com> wrote:
> > : Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid
> > : control more than anything else at that dose.!! The drug company
> > : responsible ( which one??) really need to start addressing the
> > : pharmacologic aspects of this drug. IMHO it is primarily to deal with
> > : obesity/T2 ! Very few reports suggest the contary.
> >
> > : Larry
> >
> > I don't believe tha tMetformin is used primarily as a product fo rdealing
> > with obesity. It may result in an average weight loss of about 8 lbs!
> > Not a great deal if one is obese. It deals with the release of glucagon
> > from the liver, giving you less glucose running around in the bloodstream,
> > as well as helping with insulin resistance, not pirimarily fo rweight loss
> > at all. It doesn't tend to cause you to gain weight as inculin or actos
> > and avandia can.
> >
> > Wendy