Thanks for the info Mack.
"Ma¢k" <[email protected]> wrote in message
> DRUG INTERACTIONS: Cimetidine (Tagamet), by decreasing the elimination
> of metformin from the body, can increase the amount of metformin in
> the blood by 40%. This may increase the frequency of side effects from
> SIDE EFFECTS: The most common side effects with metformin are nausea,
> vomiting, gas, bloating, diarrhea and loss of appetite. These symptoms
> occur in one out of every three patients. These side effects may be
> severe enough to cause therapy to be discontinued in one out of every
> 20 patients. These side effects are related to the dose of the
> medication and may decrease if the dose is reduced.
> A serious--though rare--side effect of metformin is lactic acidosis.
> Lactic acidosis occurs in one out of every 30,000 patients and is
> fatal in 50% of cases. The symptoms of lactic acidosis are weakness,
> trouble breathing, abnormal heartbeats, unusual muscle pain, stomach
> discomfort, light-headedness and feeling cold. Patients at risk for
> lactic acidosis include those with reduced function of the kidneys or
> liver, congestive heart failure, severe acute illnesses, and
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