Popular diabetes drug useless, even harmful, for diabetics, study suggests

http://www.newstarget.com/z020865.html

NewsTarget.com printable article
Originally published October 24 2006
Popular diabetes drug useless, even harmful, for diabetics, study suggests
(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) has
no clear-cut benefit for patients with type 2 diabetes, and may even be
harmful to users.
The scientists analyzed data from 22 clinical trials involving 6,200
patients who were prescribed pioglitazone -- a member of the
thiazolidinediones class of drugs, which theoretically increase the body's
natural insulin supply -- for type 2 diabetes. The authors reported no
evidence that the drug had a positive impact on patients, but they did note
an increase in edema and heart failure among pioglitazone users.

"The kernel from this review is that pioglitazone is effective in
glucose-lowering, has some other beneficial and potentially harmful
associated features, and just has not been evaluated in the right way to
prove that it will help people lead longer and more productive lives," said
Dr. John Buse, director of the Diabetes Care Center at the University of
North Carolina School of Medicine in Chapel Hill. "This is true for
essentially every drug available for the treatment of diabetes. I am fairly
certain that we are better off with pioglitazone than without it."

Buse said that, while the report's findings are not incorrect, more data
would be required to truly assess the drug. The report recommended that
pioglitazone only be prescribed to patients showing real benefit from the
therapy.

"Only in Western medicine would doctors respond to a study that finds a drug
to be useless with the assertion that more testing is needed, or that the
drug was not evaluated correctly," said health advocate Mike Adams. "If it
had been a vitamin or supplement found to be useless and harmful, it would
have been pulled of the shelf immediately, no questions asked. It's quite a
double standard."

Jan Drew wrote in message ...
>http://www.newstarget.com/z020865.html
>
>NewsTarget.com printable article
>Originally published October 24 2006
>Popular diabetes drug useless, even harmful, for diabetics, study suggests
>(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .
.. .

Jan Drew is a recognized net kook who posts dangerous, self-serving rants
in many health-related newsgroups.

Regards
Old Al

x-no-archive: yes

oldal4865 wrote:
> Jan Drew wrote in message ...
>
>>http://www.newstarget.com/z020865.html
>>
>>NewsTarget.com printable article
>>Originally published October 24 2006
>>Popular diabetes drug useless, even harmful, for diabetics, study suggests
>>(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .
>
> . .
>
> Jan Drew is a recognized net kook who posts dangerous, self-serving rants
> in many health-related newsgroups.
>
> Regards
> Old Al
>
>

That's all true, but if an actual citation is supplied and turns out to
be true, it doesn't negate the information contained within.

Susan

In article <4q959aFm1mvdU1@individual.net>, Susan <Susan@nothanks.org> wrote:
>x-no-archive: yes

>oldal4865 wrote:
>> Jan Drew wrote in message ...

>>>http://www.newstarget.com/z020865.html

>>>NewsTarget.com printable article
>>>Originally published October 24 2006
>>>Popular diabetes drug useless, even harmful, for diabetics, study suggests
>>>(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .

>> . .

>> Jan Drew is a recognized net kook who posts dangerous, self-serving rants
>> in many health-related newsgroups.

>> Regards
>> Old Al



>That's all true, but if an actual citation is supplied and turns out to
>be true, it doesn't negate the information contained within.

>Susan

You can get a citation about non-effectiveness about
anything which does not do something like cure a major
illness. There are no cures at this time.

The glitazones, of which Rezulin was the first, also help
in reducing insulin resistance. Rezulin did have some bad
effects in some, causing liver problems which I believe
killed one in 50,000 or so. The FDA would not have pulled
it if Avandia and Actos were not on the way to approval;
there are no safe, effective drugs. It seems that the
newer drugs cause death in a far less dramatic manner.

The other quoted material went contrary to Jan's denunciation,
and it is even the case, if one understands what is involved
in research, in pursuing drugs which seem only bad.
--
This address is for information only. I do not claim that these views
are those of the Statistics Department or of Purdue University.
Herman Rubin, Department of Statistics, Purdue University
hrubin@stat.purdue.edu Phone: (765)494-6054 FAX: (765)494-0558

oldal4865 wrote:
> Jan Drew wrote in message ...
> >http://www.newstarget.com/z020865.html
> >
> >NewsTarget.com printable article
> >Originally published October 24 2006
> >Popular diabetes drug useless, even harmful, for diabetics, study suggests
> >(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .
> . .
>
> Jan Drew is a recognized net kook who posts dangerous, self-serving rants
> in many health-related newsgroups.

Then she'll fit right in here.

Kurt

Susan <nevermind@nomail.com> wrote:

>x-no-archive: yes
>
>oldal4865 wrote:
>> Jan Drew wrote in message ...
>>
>>>http://www.newstarget.com/z020865.html
>>>
>>>NewsTarget.com printable article
>>>Originally published October 24 2006
>>>Popular diabetes drug useless, even harmful, for diabetics, study suggests
>>>(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .
>>
>> . .
>>
>> Jan Drew is a recognized net kook who posts dangerous, self-serving rants
>> in many health-related newsgroups.
>>
>> Regards
>> Old Al

I see you have met Jan, Al.

>>
>>
>
>That's all true, but if an actual citation is supplied and turns out to
>be true, it doesn't negate the information contained within.
>
>Susan

Newstarget is an exclusively anti-real-medicine publication, and the
only time any real research is reported there it is used to bash
medicine. You will note that the article in question does not give any
reference to the research that is supposed to have uncovered the
dangers of pioglitazone.

If you click on the "diabetes" link in the article you will be taken
to a collection of scare stories, all designed to make medicine look
bad. Apparently, if it can be shown that there are problems with real
medicine and real doctors then this somehow validates quackery and
snake oil.

By the way, according to PubMed, Buse hasn't published anything on
diabetes and pioglitazone since 2005 and none of the 3 papers returned
was a metastudy of 22 trials, so it could just maybe be a lie that is
being spread by Newstarget and Mike Adams. Whoda thunk it?
--
Peter Bowditch aa #2243
The Millenium Project http://www.ratbags.com/rsoles
Australian Council Against Health Fraud http://www.acahf.org.au
Australian Skeptics http://www.skeptics.com.au
To email me use my first name only at ratbags.com

"Kurt" <kurtwheeling1965@hotmail.com> wrote:

>oldal4865 wrote:
>> Jan Drew wrote in message ...
>> >http://www.newstarget.com/z020865.html
>> >
>> >NewsTarget.com printable article
>> >Originally published October 24 2006
>> >Popular diabetes drug useless, even harmful, for diabetics, study suggests
>> >(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .
>> . .
>>
>> Jan Drew is a recognized net kook who posts dangerous, self-serving rants
>> in many health-related newsgroups.
>
>Then she'll fit right in here.
>
>Kurt

Please, no! I have enough trouble being continually accused of lying
in other groups without it starting here as well. Also, she will
mercilessly crosspost stuff to where it is neither relevant nor
wanted. As an example, her reply to a recent post I made in
sci.med.dentistry was crossposted to misc.health.alternative,
alt.support.breast-implant, misc.headlines, talk.politics.medicine and
sci.med. the fact that she changed the subject line to say "Peter
Bowditch's Deceitfulness" was a bonus.
--
Peter Bowditch aa #2243
The Millenium Project http://www.ratbags.com/rsoles
Australian Council Against Health Fraud http://www.acahf.org.au
Australian Skeptics http://www.skeptics.com.au
To email me use my first name only at ratbags.com

x-no-archive: yes

Peter Bowditch wrote:
> Susan <nevermind@nomail.com> wrote:
>
>
>>x-no-archive: yes
>>
>>oldal4865 wrote:
>>
>>>Jan Drew wrote in message ...
>>>
>>>
>>>>http://www.newstarget.com/z020865.html
>>>>
>>>>NewsTarget.com printable article
>>>>Originally published October 24 2006
>>>>Popular diabetes drug useless, even harmful, for diabetics, study suggests
>>>>(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .
>>>
>>>. .
>>>
>>>Jan Drew is a recognized net kook who posts dangerous, self-serving rants
>>>in many health-related newsgroups.
>>>
>>>Regards
>>> Old Al
>
>
> I see you have met Jan, Al.
>
>
>>>
>>That's all true, but if an actual citation is supplied and turns out to
>>be true, it doesn't negate the information contained within.
>>
>>Susan
>
>
> Newstarget is an exclusively anti-real-medicine publication, and the
> only time any real research is reported there it is used to bash
> medicine. You will note that the article in question does not give any
> reference to the research that is supposed to have uncovered the
> dangers of pioglitazone.
>
> If you click on the "diabetes" link in the article you will be taken
> to a collection of scare stories, all designed to make medicine look
> bad. Apparently, if it can be shown that there are problems with real
> medicine and real doctors then this somehow validates quackery and
> snake oil.
>
> By the way, according to PubMed, Buse hasn't published anything on
> diabetes and pioglitazone since 2005 and none of the 3 papers returned
> was a metastudy of 22 trials, so it could just maybe be a lie that is
> being spread by Newstarget and Mike Adams. Whoda thunk it?

Yes, I saw that newstarget cite provided no journal citation.

I agree that Jan is nutty.

My only point is that when citations are provided by nuts, even, they
may be worth evaluating on their own. We weren't given one this time.

Susan

Susan <nevermind@nomail.com> wrote:

>x-no-archive: yes
>
>Peter Bowditch wrote:
>> Susan <nevermind@nomail.com> wrote:
>>
>>
>>>x-no-archive: yes
>>>
>>>oldal4865 wrote:
>>>
>>>>Jan Drew wrote in message ...
>>>>
>>>>
>>>>>http://www.newstarget.com/z020865.html
>>>>>
>>>>>NewsTarget.com printable article
>>>>>Originally published October 24 2006
>>>>>Popular diabetes drug useless, even harmful, for diabetics, study suggests
>>>>>(NewsTarget) A recent study notes the diabetes drug pioglitazone (Actos) .
>>>>
>>>>. .
>>>>
>>>>Jan Drew is a recognized net kook who posts dangerous, self-serving rants
>>>>in many health-related newsgroups.
>>>>
>>>>Regards
>>>> Old Al
>>
>>
>> I see you have met Jan, Al.
>>
>>
>>>>
>>>That's all true, but if an actual citation is supplied and turns out to
>>>be true, it doesn't negate the information contained within.
>>>
>>>Susan
>>
>>
>> Newstarget is an exclusively anti-real-medicine publication, and the
>> only time any real research is reported there it is used to bash
>> medicine. You will note that the article in question does not give any
>> reference to the research that is supposed to have uncovered the
>> dangers of pioglitazone.
>>
>> If you click on the "diabetes" link in the article you will be taken
>> to a collection of scare stories, all designed to make medicine look
>> bad. Apparently, if it can be shown that there are problems with real
>> medicine and real doctors then this somehow validates quackery and
>> snake oil.
>>
>> By the way, according to PubMed, Buse hasn't published anything on
>> diabetes and pioglitazone since 2005 and none of the 3 papers returned
>> was a metastudy of 22 trials, so it could just maybe be a lie that is
>> being spread by Newstarget and Mike Adams. Whoda thunk it?
>
>Yes, I saw that newstarget cite provided no journal citation.
>
>I agree that Jan is nutty.
>
>My only point is that when citations are provided by nuts, even, they
>may be worth evaluating on their own. We weren't given one this time.
>
>Susan

I have been observing Jan for several years. In that time she has
posted zero links with useful content unless it was done by accident
because she didn't understand the title. Within the last week she was
posting stories about how dreadful it was that children who had been
cured of cancer caught diseases later in life. She would not accept
that a live child was much more likely to become a sick adult than a
dead child would be, but she saw the story only as one about how
cancer treatment caused problems later in life. Do not ever try to
have any sort of discussion with her about ADHD or amalgam.

Newstarget is never a useful reference. If a truth got in there it
would be by accident.
--
Peter Bowditch aa #2243
The Millenium Project http://www.ratbags.com/rsoles
Australian Council Against Health Fraud http://www.acahf.org.au
Australian Skeptics http://www.skeptics.com.au
To email me use my first name only at ratbags.com