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Old 09-12-2007, 03:42 PM
Andrew B. Chung, MD/PhD
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Default Re: ...another human influenza pandemic is inevitable...

convicted neighbor Don Kirkman wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> >convicted neighbor Cary Kittrell wrote:

>
> >> Not exactly what the WHO director general said

>
> >Did not write that it was what the WHO director general said but
> >rather:

>
> >"Actually there has only been one bird-->human influenza pandemic
> >during the last century" -- Andrew, in the Holy Spirit.

>
> That may not be as clear-cut as you imply


It actually is thanks to both the little Enza limmerick that has
survived to serve as a reminder that survivors had made the
observation that birds carried the virus to humans and to the fact
that "the 1918 HA is virtually identical to the consensus sequence of
avian strains" (see below).

> (and AAR the current avian flu
> strain seems to be different from the Spanish flu of 1918):


(The current H5N1 avian Flu strain appears to be more pathogenic in
humans than the 1918 avian Flu strain with a possible population kill
rate of near 100% without treatment).

> [Begin]
> We have analyzed the 1918 strain's NA gene in a continuation of our work
> to characterize the 1918 influenza virus. Previous phylogenetic analyses
> of the complete 1918 HA gene (7) place the 1918 strain within and near
> the root of the mammalian clade. This placement suggests that the 1918
> HA shares many characteristics with subsequent human and swine strains.
> Nevertheless, the 1918 HA is more closely related to avian HAs than any
> other mammalian strain, and it shares many structural characteristics
> with avian isolates. It has only the four glycosylation sites conserved
> in all H1 HAs and none of the additional sites that have accumulated by
> antigenic drift in human strains over time. In the areas of H1 that have
> been identified as antigenic in humans, the 1918 HA is virtually
> identical to the consensus sequence of avian strains, whereas human
> strains from 1933 on show extensive drift at these sites. Overall, the
> results of the HA analyses suggest either that the 1918 strain entered
> the human population directly from birds (but that modern bird strains
> have drifted from their 1918 sequences) or that the 1918 strain entered
> a mammalian host in the years immediately preceding 1918 and adapted
> there before emerging as a pandemic virus. A similar scenario appears to
> be true for the virus' NA gene.
> [End]
> http://www.pubmedcentral.nih.gov/art...i?&artid=18739


The fact that "the 1918 HA is virtually identical to the consensus
sequence of avian strains" allows a molecular biologist to be certain
that that the 1918 Pan-Flu virus was an avian virus.

Truth is simple.

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

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  #2  
Old 09-13-2007, 02:14 AM
Andrew B. Chung, MD/PhD
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Posts: n/a
Default Re: ...another human influenza pandemic is inevitable...

convicted neighbor Don Kirkman wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> >convicted neighbor Don Kirkman wrote:
> >> Andrew, in the Holy Spirit, boldly wrote:

>
> >> >"Actually there has only been one bird-->human influenza pandemic
> >> >during the last century" -- Andrew, in the Holy Spirit.

>
> >> That may not be as clear-cut as you imply

>
> > It actually is thanks to both the little Enza limerick that has
> > survived to serve as a reminder that survivors had made the
> > observation that birds carried the virus to humans and to the fact
> > that "the 1918 HA is virtually identical to the consensus sequence of
> > Avian strains" (see below).

>
> You'll never make it as a poet, either.


Have not written that I were the author of the little Enza limerick.

>The ditty is not a limerick,
> which has a five-line AABBA structure, not the four lines of "Enza"
>
> I had a little bird/
> Its name was Enza/
> I opened up the window/
> and in flew enza.


This reminds me of how the 2PD-OMER Approach is not a diet.

Seems curious that you are strict about what are limericks but not
about what are diets :-)

> Although PBS used that in a broadcast about *the current* avian flu
> scare, they didn't document its source, nor have I found it (yet). My
> parents' generation lived through the 1918 Spanish flu (one brother died
> of it during military service) but they never mentioned such a ditty,
> one which seems oddly out of character for a time of dreaded illness.
>
> Either way, a child's game ditty has zero evidentiary value about the
> provenance or probability of avian flue.


Not for the discerning especially in the context of the 1918 Pan-Flu
virus having a genetic sequence virtually identical to the avian
consensus sequence.

> >> (and AAR the current avian flu
> >> strain seems to be different from the Spanish flu of 1918):

>
> >(The current H5N1 avian Flu strain appears to be more pathogenic in
> >humans than the 1918 avian Flu strain with a possible population kill
> >rate of near 100% without treatment).

>
> Appears to whom? Citations? How many deaths have been caused by it so
> far? How many were acquired from fowl and how many from human contact?


Would suggest you reread what the Holy Spirit has guided me to write
as many times as you require to understand it.

> >> [Begin]
> >> We have analyzed the 1918 strain's NA gene in a continuation of our work
> >> to characterize the 1918 influenza virus. Previous phylogenetic analyses
> >> of the complete 1918 HA gene (7) place the 1918 strain within and near
> >> the root of the mammalian clade. This placement suggests that the 1918
> >> HA shares many characteristics with subsequent human and swine strains.
> >> Nevertheless, the 1918 HA is more closely related to avian HAs than any
> >> other mammalian strain, and it shares many structural characteristics
> >> with avian isolates. It has only the four glycosylation sites conserved
> >> in all H1 HAs and none of the additional sites that have accumulated by
> >> antigenic drift in human strains over time. In the areas of H1 that have
> >> been identified as antigenic in humans, the 1918 HA is virtually
> >> identical to the consensus sequence of avian strains, whereas human
> >> strains from 1933 on show extensive drift at these sites. Overall, the
> >> results of the HA analyses suggest either that the 1918 strain entered
> >> the human population directly from birds (but that modern bird strains
> >> have drifted from their 1918 sequences) or that the 1918 strain entered
> >> a mammalian host in the years immediately preceding 1918 and adapted
> >> there before emerging as a pandemic virus. A similar scenario appears to
> >> be true for the virus' NA gene.
> >> [End]
> >> http://www.pubmedcentral.nih.gov/art...i?&artid=18739

>
> >The fact that "the 1918 HA is virtually identical to the consensus
> >sequence of avian strains" allows a molecular biologist to be certain
> >that that the 1918 Pan-Flu virus was an avian virus.

>
> Which, the cite says, suggests "either that the 1918 strain entered
> directly from birds [but modern strains are already different] **or**
> that the 1918 strain entered a mammalian host **and adapted**" before
> humans were infected by it.


In either case scenario, the 1918 Pan-Flu virus would remain avian in
origin.

> >Truth is simple.

>
> Yes; try some.


It remains my choice to continue writing truthfully.

It is my hope that you have committed the information contained on the
DVD that you have received from the Wellness Foundation to memory so
that you are prepared for the influenza pandemic when it occurs as
anticipated even in the worst case scenario of about 60% lethality
with treatment and near 100% without treatment.

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

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