Re: Insulin resistance & Downregulation?

convicted friend Kumar wrote:
>
> "Downregulation
> Cases
> To illustrate this process we shall look at the insulin receptor sites
> on the target cells of a type 2 diabetic. Due to the elevated levels
> of blood glucose from excessive feeding in an overweight individual
> the β-cells (islets of Langerhans) in the pancreas must release more
> insulin than normally emitted to match the demand and return the blood
> to homeostatic levels.

Incorrect.

The reason for hyperinsulinemia in this setting is pre-existing
insulin resistance (IR/MetS) because of the presence of bad "inside"
fat (visceral adipose tissue or VAT) which is the primary source of
the pro-inflammatory cytokines that directly cause IR/MetS.

Whenever we overeat (stomach stretched killing the hunger) we
accumulate VAT.

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

On Aug 23, 3:25Â*pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> convicted friend Kumar wrote:
>
> > "Downregulation
> > Cases
> > To illustrate this process we shall look at the insulin receptor sites
> > on the target cells of a type 2 diabetic. Due to the elevated levels
> > of blood glucose from excessive feeding in an overweight individual
> > the β-cells (islets of Langerhans) in the pancreas must release more
> > insulin than normally emitted to match the demand and return the blood
> > to homeostatic levels.
>
> Incorrect.
>
> The reason for hyperinsulinemia in this setting is pre-existing
> insulin resistance (IR/MetS) because of the presence of bad "inside"
> fat (visceral adipose tissue or VAT) which is the primary source of
> the pro-inflammatory cytokines that directly cause IR/MetS.
>
> Whenever we overeat (stomach stretched killing the hunger) we
> accumulate VAT.
>
> Be hungry... be healthy... be hungrier... be blessed:
>
> http://TheWellnessFoundation.com/PressRelease
>
> Prayerfully in Jesus' awesome love,
>
> Andrew <><
> --
> Andrew B. Chung, MD/PhD
> Cardiologist

Greetings!!, Why can't body get physiological tolerances or resistance
to increased insulin's exposure secreted due to persisting higher
glucose levels in IR cases? Excessive fats can also be an expression
of excessive energy available, so may cause mecanisms to balance
these, one may be such inflamatory response?

convicted friend Kumar wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> > convicted friend Kumar wrote:
> >
> > > "Downregulation
> > > Cases
> > > To illustrate this process we shall look at the insulin receptor sites
> > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > of blood glucose from excessive feeding in an overweight individual
> > > the β-cells (islets of Langerhans) in the pancreas must release more
> > > insulin than normally emitted to match the demand and return the blood
> > > to homeostatic levels.
> >
> > Incorrect.
> >
> > The reason for hyperinsulinemia in this setting is pre-existing
> > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > fat (visceral adipose tissue or VAT) which is the primary source of
> > the pro-inflammatory cytokines that directly cause IR/MetS.
> >
> > Whenever we overeat (stomach stretched killing the hunger) we
> > accumulate VAT.
> >
> > Be hungry... be healthy... be hungrier... be blessed:
> >
> > http://TheWellnessFoundation.com/PressRelease
>
> Greetings!!

Hi :-)

>, Why can't body get physiological tolerances or resistance
> to increased insulin's exposure secreted due to persisting higher
> glucose levels in IR cases?

It simply is not what is happening.

> Excessive fats can also be an expression
> of excessive energy available, so may cause mecanisms to balance
> these, one may be such inflamatory response?

It is simply the nature of the bad "inside" fat (visceral adipose
tissue or VAT) to be completely pathological.

May GOD bless you in HIS mighty way making you healthier (hungrier)
than ever:

http://HeartMDPhD.com/HolySpirit/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

On Aug 23, 6:51Â*pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> convicted friend Kumar wrote:
> > Andrew, in the Holy Spirit, boldly wrote:
> > > convicted friend Kumar wrote:
>
> > > > "Downregulation
> > > > Cases
> > > > To illustrate this process we shall look at the insulin receptor sites
> > > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > > of blood glucose from excessive feeding in an overweight individual
> > > > the β-cells (islets of Langerhans) in the pancreas must release more
> > > > insulin than normally emitted to match the demand and return the blood
> > > > to homeostatic levels.
>
> > > Incorrect.
>
> > > The reason for hyperinsulinemia in this setting is pre-existing
> > > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > the pro-inflammatory cytokines that directly cause IR/MetS.
>
> > > Whenever we overeat (stomach stretched killing the hunger) we
> > > accumulate VAT.
>
> > > Be hungry... be healthy... be hungrier... be blessed:
>
> > >http://TheWellnessFoundation.com/PressRelease
>
> > Greetings!!
>
> Hi :-)
>
> >, Why can't body get physiological tolerances or resistance
> > to increased insulin's exposure secreted due to persisting higher
> > glucose levels in IR cases?
>
> It simply is not what is happening.
How/why downregulation of insulin's receptors take place?
> > Excessive fats can also be an expression
> > of excessive energy available, so may cause mecanisms to balance
> > these, one may be such inflamatory response?
>
> It is simply the nature of the bad "inside" fat (visceral adipose
> tissue or VAT) to be completely pathological.
Do VATS not provide insulation, increased transcapillary movements and
energy?
> May GOD bless you in HIS mighty way making you healthier (hungrier)
> than ever:
>
> http://HeartMDPhD.com/HolySpirit/PressRelease
>
> Prayerfully in Jesus' awesome love,
>
> Andrew <><
> --
> Andrew B. Chung, MD/PhD
> Cardiologist- Hide quoted text -
>
> - Show quoted text -

convicted friend Kumar wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> > convicted friend Kumar wrote:
> > > Andrew, in the Holy Spirit, boldly wrote:
> > > > convicted friend Kumar wrote:
> >
> > > > > "Downregulation
> > > > > Cases
> > > > > To illustrate this process we shall look at the insulin receptor sites
> > > > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > > > of blood glucose from excessive feeding in an overweight individual
> > > > > the β-cells (islets of Langerhans) in the pancreas must release more
> > > > > insulin than normally emitted to match the demand and return the blood
> > > > > to homeostatic levels.
> >
> > > > Incorrect.
> >
> > > > The reason for hyperinsulinemia in this setting is pre-existing
> > > > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > > the pro-inflammatory cytokines that directly cause IR/MetS.
> >
> > > > Whenever we overeat (stomach stretched killing the hunger) we
> > > > accumulate VAT.
> >
> > > > Be hungry... be healthy... be hungrier... be blessed:
> >
> > > >http://TheWellnessFoundation.com/PressRelease
> >
> > > Greetings!!
> >
> > Hi :-)
> >
> > >, Why can't body get physiological tolerances or resistance
> > > to increased insulin's exposure secreted due to persisting higher
> > > glucose levels in IR cases?
> >
> > It simply is not what is happening.
>
> How/why downregulation of insulin's receptors take place?

Pro-inflammatory cytokines from VAT cause the impairment of insulin
response at both the receptor and signalling levels.

> > > Excessive fats can also be an expression
> > > of excessive energy available, so may cause mecanisms to balance
> > > these, one may be such inflamatory response?
> >
> > It is simply the nature of the bad "inside" fat (visceral adipose
> > tissue or VAT) to be completely pathological.
>
> Do VATS not provide insulation, increased transcapillary movements and
> energy?

VAT is not SAT.

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

On Aug 24, 2:34Â*pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> convicted friend Kumar wrote:
> > Andrew, in the Holy Spirit, boldly wrote:
> > > convicted friend Kumar wrote:
> > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > convicted friend Kumar wrote:
>
> > > > > > "Downregulation
> > > > > > Cases
> > > > > > To illustrate this process we shall look at the insulin receptor sites
> > > > > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > > > > of blood glucose from excessive feeding in an overweight individual
> > > > > > the β-cells (islets of Langerhans) in the pancreas must release more
> > > > > > insulin than normally emitted to match the demand and return the blood
> > > > > > to homeostatic levels.
>
> > > > > Incorrect.
>
> > > > > The reason for hyperinsulinemia in this setting is pre-existing
> > > > > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > > > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > > > the pro-inflammatory cytokines that directly cause IR/MetS.
>
> > > > > Whenever we overeat (stomach stretched killing the hunger) we
> > > > > accumulate VAT.
>
> > > > > Be hungry... be healthy... be hungrier... be blessed:
>
> > > > >http://TheWellnessFoundation.com/PressRelease
>
> > > > Greetings!!
>
> > > Hi :-)
>
> > > >, Why can't body get physiological tolerances or resistance
> > > > to increased insulin's exposure secreted due to persisting higher
> > > > glucose levels in IR cases?
>
> > > It simply is not what is happening.
>
> > How/why downregulation of insulin's receptors take place?
>
> Pro-inflammatory cytokines from VAT cause the impairment of insulin
> response at both the receptor and signalling levels.
Whether VAT or its inflammatory response is a signal of excessive
availabilty of energy stores, on which body's mechanism are active to
reverse?
> > > > Excessive fats can also be an expression
> > > > of excessive energy available, so may cause mecanisms to balance
> > > > these, one may be such inflamatory response?
>
> > > It is simply the nature of the bad "inside" fat (visceral adipose
> > > tissue or VAT) to be completely pathological.
>
> > Do VATS not provide insulation, increased transcapillary movements and
> > energy?
>
> VAT is not SAT.
VAT may be an insulation to viscera/organs? Immediate energy can be
released on utilizing these and I think inflammatory responses are
related to increased transcapillarry movements?
> Be hungry... be healthy... be hungrier... be blessed:
>
> http://TheWellnessFoundation.com/PressRelease
>
> Prayerfully in Jesus' awesome love,
>
> Andrew <><
> --
> Andrew B. Chung, MD/PhD
> Cardiologist- Hide quoted text -
>
> - Show quoted text -

convicted neighbor Kumar wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> > convicted friend Kumar wrote:
> > > Andrew, in the Holy Spirit, boldly wrote:
> > > > convicted friend Kumar wrote:
> > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > convicted friend Kumar wrote:
> >
> > > > > > > "Downregulation
> > > > > > > Cases
> > > > > > > To illustrate this process we shall look at the insulin receptor sites
> > > > > > > on the target cells of a type 2 diabetic. Due to the elevatedlevels
> > > > > > > of blood glucose from excessive feeding in an overweight individual
> > > > > > > the β-cells (islets of Langerhans) in the pancreas must release more
> > > > > > > insulin than normally emitted to match the demand and return the blood
> > > > > > > to homeostatic levels.
> >
> > > > > > Incorrect.
> >
> > > > > > The reason for hyperinsulinemia in this setting is pre-existing
> > > > > > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > > > > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > > > > the pro-inflammatory cytokines that directly cause IR/MetS.
> >
> > > > > > Whenever we overeat (stomach stretched killing the hunger) we
> > > > > > accumulate VAT.
> >
> > > > > > Be hungry... be healthy... be hungrier... be blessed:
> >
> > > > > >http://TheWellnessFoundation.com/PressRelease
> >
> > > > > Greetings!!
> >
> > > > Hi :-)
> >
> > > > >, Why can't body get physiological tolerances or resistance
> > > > > to increased insulin's exposure secreted due to persisting higher
> > > > > glucose levels in IR cases?
> >
> > > > It simply is not what is happening.
> >
> > > How/why downregulation of insulin's receptors take place?
> >
> > Pro-inflammatory cytokines from VAT cause the impairment of insulin
> > response at both the receptor and signalling levels.
> Whether VAT or its inflammatory response is a signal of excessive
> availabilty of energy stores, on which body's mechanism are active to
> reverse?
> > > > > Excessive fats can also be an expression
> > > > > of excessive energy available, so may cause mecanisms to balance
> > > > > these, one may be such inflamatory response?
> >
> > > > It is simply the nature of the bad "inside" fat (visceral adipose
> > > > tissue or VAT) to be completely pathological.
> >
> > > Do VATS not provide insulation, increased transcapillary movements and
> > > energy?
> >
> > VAT is not SAT.
>
> VAT may be an insulation to viscera/organs?

It is not. Organs have visceral pleura to serve as "insulation."

> Immediate energy can be
> released on utilizing these and I think inflammatory responses are
> related to increased transcapillarry movements?

Fat does not serve as immediate energy.

The inflammation promoted by VAT serves only to cause harm.

May GOD bless you in HIS mighty way making you healthier (hungrier)
than ever:

http://HeartMDPhD.com/HolySpirit/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

Before considering accepting or acting upon the opinions of andrew chung
on any topic, please read at least 3 of his other posts. Quickly you
will percieve clearly the truth of this warning. Any question his
opinion might suggest to you should be confirmed always with an expert
or others in the newsgroup.

On Aug 24, 4:16Â*pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> convicted neighbor Kumar wrote:
> > Andrew, in the Holy Spirit, boldly wrote:
> > > convicted friend Kumar wrote:
> > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > convicted friend Kumar wrote:
> > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > convicted friend Kumar wrote:
>
> > > > > > > > "Downregulation
> > > > > > > > Cases
> > > > > > > > To illustrate this process we shall look at the insulin receptor sites
> > > > > > > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > > > > > > of blood glucose from excessive feeding in an overweight individual
> > > > > > > > the β-cells (islets of Langerhans) in the pancreas must release more
> > > > > > > > insulin than normally emitted to match the demand and return the blood
> > > > > > > > to homeostatic levels.
>
> > > > > > > Incorrect.
>
> > > > > > > The reason for hyperinsulinemia in this setting is pre-existing
> > > > > > > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > > > > > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > > > > > the pro-inflammatory cytokines that directly cause IR/MetS.
>
> > > > > > > Whenever we overeat (stomach stretched killing the hunger) we
> > > > > > > accumulate VAT.
>
> > > > > > > Be hungry... be healthy... be hungrier... be blessed:
>
> > > > > > >http://TheWellnessFoundation.com/PressRelease
>
> > > > > > Greetings!!
>
> > > > > Hi :-)
>
> > > > > >, Why can't body get physiological tolerances or resistance
> > > > > > to increased insulin's exposure secreted due to persisting higher
> > > > > > glucose levels in IR cases?
>
> > > > > It simply is not what is happening.
>
> > > > How/why downregulation of insulin's receptors take place?
>
> > > Pro-inflammatory cytokines from VAT cause the impairment of insulin
> > > response at both the receptor and signalling levels.
> > Whether VAT or its inflammatory response is a signal of excessive
> > availabilty of energy stores, on which body's mechanism are active to
> > reverse?
> > > > > > Excessive fats can also be an expression
> > > > > > of excessive energy available, so may cause mecanisms to balance
> > > > > > these, one may be such inflamatory response?
>
> > > > > It is simply the nature of the bad "inside" fat (visceral adipose
> > > > > tissue or VAT) to be completely pathological.
>
> > > > Do VATS not provide insulation, increased transcapillary movements and
> > > > energy?
>
> > > VAT is not SAT.
>
> > VAT may be an insulation to viscera/organs?
>
> It is not. Â*Organs have visceral pleura to serve as "insulation."
Additional isulation and to hold visceral pleura?
What can cause, organs to get additional insulation?
> > Immediate energy can be
> > released on utilizing these and I think inflammatory responses are
> > related to increased transcapillarry movements?
Insulin's one action is to enhance transcapillary movements by
relaxing vascular tone?
> Fat does not serve as immediate energy.
Earlier than energy from SAT, if glucose is less efficient due to IR?
> The inflammation promoted by VAT serves only to cause harm.
Can our body need such inflammation for any purpose?
> May GOD bless you in HIS mighty way making you healthier (hungrier)
> than ever:
Thanks.
> http://HeartMDPhD.com/HolySpirit/PressRelease
>
> Prayerfully in Jesus' awesome love,
>
> Andrew <><
> --
> Andrew B. Chung, MD/PhD
> Cardiologist- Hide quoted text -
>
> - Show quoted text -

On Aug 24, 9:28 pm, tr...@is-best.com wrote:
> Before considering accepting or acting upon the opinions of andrew chung
> on any topic, please read at least 3 of his other posts. Quickly you
> will percieve clearly the truth of this warning. Any question his
> opinion might suggest to you should be confirmed always with an expert
> or others in the newsgroup.

Thanks but I understand him since long back. Still I need replies from
others.

On Aug 24, 7:58�pm, Kumar <lordshiva5...@gmail.com> wrote:
> On Aug 24, 4:16*pm, "Andrew B. Chung, MD/PhD"
>
>
>
> <heartdo...@emorycardiology.com> wrote:
> > convicted neighbor Kumar wrote:
> > > Andrew, in the Holy Spirit, boldly wrote:
> > > > convicted friend Kumar wrote:
> > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > convicted friend Kumar wrote:
> > > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > > convicted friend Kumar wrote:
>
> > > > > > > > > "Downregulation
> > > > > > > > > Cases
> > > > > > > > > To illustrate this process we shall look at the insulin receptor sites
> > > > > > > > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > > > > > > > of blood glucose from excessive feeding in an overweight individual
> > > > > > > > > the -cells (islets of Langerhans) in the pancreas must release more
> > > > > > > > > insulin than normally emitted to match the demand and return the blood
> > > > > > > > > to homeostatic levels.
>
> > > > > > > > Incorrect.
>
> > > > > > > > The reason for hyperinsulinemia in this setting is pre-existing
> > > > > > > > insulin resistance (IR/MetS) because of the presence of bad"inside"
> > > > > > > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > > > > > > the pro-inflammatory cytokines that directly cause IR/MetS.
>
> > > > > > > > Whenever we overeat (stomach stretched killing the hunger) we
> > > > > > > > accumulate VAT.
>
> > > > > > > > Be hungry... be healthy... be hungrier... be blessed:
>
> > > > > > > >http://TheWellnessFoundation.com/PressRelease
>
> > > > > > > Greetings!!
>
> > > > > > Hi :-)
>
> > > > > > >, Why can't body get physiological tolerances or resistance
> > > > > > > to increased insulin's exposure secreted due to persisting higher
> > > > > > > glucose levels in IR cases?
>
> > > > > > It simply is not what is happening.
>
> > > > > How/why downregulation of insulin's receptors take place?
>
> > > > Pro-inflammatory cytokines from VAT cause the impairment of insulin
> > > > response at both the receptor and signalling levels.
> > > Whether VAT or its inflammatory response is a signal of excessive
> > > availabilty of energy stores, on which body's mechanism are active to
> > > reverse?
> > > > > > > Excessive fats can also be an expression
> > > > > > > of excessive energy available, so may cause mecanisms to balance
> > > > > > > these, one may be such inflamatory response?
>
> > > > > > It is simply the nature of the bad "inside" fat (visceral adipose
> > > > > > tissue or VAT) to be completely pathological.
>
> > > > > Do VATS not provide insulation, increased transcapillary movements and
> > > > > energy?
>
> > > > VAT is not SAT.
>
> > > VAT may be an insulation to viscera/organs?
>
> > It is not. *Organs have visceral pleura to serve as "insulation."
>
> Additional isulation and to hold visceral pleura?
> What can cause, organs to get additional insulation?> > Immediate energy can be
> > > released on utilizing these and I think inflammatory responses are
> > > related to increased transcapillarry movements?
>
> *Insulin's one action is to enhance transcapillary movements by
> relaxing vascular tone?> Fat does not serve as immediate energy.
>
> Earlier than energy from SAT, if glucose is less efficient due to IR?> The inflammation promoted by VAT serves only to cause harm.
>
> Can our body need such inflammation for any purpose?
>
>
>
> > May GOD bless you in HIS mighty way making you healthier (hungrier)
> > than ever:
> Thanks.
> >http://HeartMDPhD.com/HolySpirit/PressRelease
>
> > Prayerfully in Jesus' awesome love,
>
> > Andrew <><
> > --
> > Andrew B. Chung, MD/PhD
> > Cardiologist- Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -- Hide quoted text -
>
> - Show quoted text -

Kumar: I should remind you that the issue of VAT is not relevant so
much to all types of T2 diabetes. As you know T2 is a heterogenous
disease mostly (80%) VAT related but there are other issues to address
in treating this disease. Fat is just part of the problem in some
patients.

Larry

Larry wrote:
> Convicted friend Kumar <lordshiva5...@gmail.com> wrote:
> > Andrew, in the Holy Spirit, boldly wrote:
> > > convicted neighbor Kumar wrote:
> > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > convicted friend Kumar wrote:
> > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > convicted friend Kumar wrote:
> > > > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > > > convicted friend Kumar wrote:
> >
> > > > > > > > > > "Downregulation
> > > > > > > > > > Cases
> > > > > > > > > > To illustrate this process we shall look at the insulin receptor sites
> > > > > > > > > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > > > > > > > > of blood glucose from excessive feeding in an overweight individual
> > > > > > > > > > the -cells (islets of Langerhans) in the pancreas must release more
> > > > > > > > > > insulin than normally emitted to match the demand and return the blood
> > > > > > > > > > to homeostatic levels.
> >
> > > > > > > > > Incorrect.
> >
> > > > > > > > > The reason for hyperinsulinemia in this setting is pre-existing
> > > > > > > > > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > > > > > > > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > > > > > > > the pro-inflammatory cytokines that directly cause IR/MetS.
> >
> > > > > > > > > Whenever we overeat (stomach stretched killing the hunger) we
> > > > > > > > > accumulate VAT.
> >
> > > > > > > > > Be hungry... be healthy... be hungrier... be blessed:
> >
> > > > > > > > >http://TheWellnessFoundation.com/PressRelease
> >
> > > > > > > > Greetings!!
> >
> > > > > > > Hi :-)
> >
> > > > > > > >, Why can't body get physiological tolerances or resistance
> > > > > > > > to increased insulin's exposure secreted due to persisting higher
> > > > > > > > glucose levels in IR cases?
> >
> > > > > > > It simply is not what is happening.
> >
> > > > > > How/why downregulation of insulin's receptors take place?
> >
> > > > > Pro-inflammatory cytokines from VAT cause the impairment of insulin
> > > > > response at both the receptor and signalling levels.
>
> > > > Whether VAT or its inflammatory response is a signal of excessive
> > > > availabilty of energy stores, on which body's mechanism are active to
> > > > reverse?
>
> > > > > > > > Excessive fats can also be an expression
> > > > > > > > of excessive energy available, so may cause mecanisms to balance
> > > > > > > > these, one may be such inflamatory response?
> >
> > > > > > > It is simply the nature of the bad "inside" fat (visceral adipose
> > > > > > > tissue or VAT) to be completely pathological.
> >
> > > > > > Do VATS not provide insulation, increased transcapillary movements and
> > > > > > energy?
> >
> > > > > VAT is not SAT.
> >
> > > > VAT may be an insulation to viscera/organs?
> >
> > > It is not. ?Organs have visceral pleura to serve as "insulation."
> >
> > Additional isulation and to hold visceral pleura?
> > What can cause, organs to get additional insulation?
> > Immediate energy can be
> > > > released on utilizing these and I think inflammatory responses are
> > > > related to increased transcapillarry movements?
> >
> > ?Insulin's one action is to enhance transcapillary movements by
> > relaxing vascular tone?> Fat does not serve as immediate energy.
> >
> > Earlier than energy from SAT, if glucose is less efficient due to IR?
>
> > >The inflammation promoted by VAT serves only to cause harm.
> >
> > Can our body need such inflammation for any purpose?
> >
> > > May GOD bless you in HIS mighty way making you healthier (hungrier)
> > > than ever:
>
> > Thanks.
>
> > >http://HeartMDPhD.com/HolySpirit/PressRelease
>
> Kumar: I should remind you that the issue of VAT is not relevant so
> much to all types of T2 diabetes.

By definition, type-2 diabetes is a problem of insulin resistance that
is complicated by secondary pancreatic (beta islet cell)
insufficiency.

It is also known that VAT is the cause of insulin resistance (IR/
MetS).

It logically follows that VAT is relevant to every instance of type-2
diabetes.

Indeed, there is VAT present in every instance of type-2 diabetes.

> As you know T2 is a heterogenous disease

Not where IR/MetS is concerned.

> mostly (80%) VAT related

IR/MetS is 100% VAT related.

> but there are other issues to address
> in treating this disease.

Only while addressing the cause in hopes of achieving a cure.

> Fat is just part of the problem in some
> patients.

VAT is not just fat... it is the bad "inside" fat that is completely
pathological, where only a few ounces can confer IR/MetS.

Folks with IR/MetS invariably have large WHRs (Waist to Hip Ratios):

Greater than 0.75 (women).

Greater than 0.85 (men).

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

On Aug 25, 8:12 am, Larry <boelk...@aol.com> wrote:
> On Aug 24, 7:58?pm, Kumar <lordshiva5...@gmail.com> wrote:
>
>
>
>
>
> > On Aug 24, 4:16?pm, "Andrew B. Chung, MD/PhD"
>
> > <heartdo...@emorycardiology.com> wrote:
> > > convicted neighbor Kumar wrote:
> > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > convicted friend Kumar wrote:
> > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > convicted friend Kumar wrote:
> > > > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > > > convicted friend Kumar wrote:
>
> > > > > > > > > > "Downregulation
> > > > > > > > > > Cases
> > > > > > > > > > To illustrate this process we shall look at the insulin receptor sites
> > > > > > > > > > on the target cells of a type 2 diabetic. Due to the elevated levels
> > > > > > > > > > of blood glucose from excessive feeding in an overweight individual
> > > > > > > > > > the -cells (islets of Langerhans) in the pancreas must release more
> > > > > > > > > > insulin than normally emitted to match the demand and return the blood
> > > > > > > > > > to homeostatic levels.
>
> > > > > > > > > Incorrect.
>
> > > > > > > > > The reason for hyperinsulinemia in this setting is pre-existing
> > > > > > > > > insulin resistance (IR/MetS) because of the presence of bad "inside"
> > > > > > > > > fat (visceral adipose tissue or VAT) which is the primary source of
> > > > > > > > > the pro-inflammatory cytokines that directly cause IR/MetS.
>
> > > > > > > > > Whenever we overeat (stomach stretched killing the hunger) we
> > > > > > > > > accumulate VAT.
>
> > > > > > > > > Be hungry... be healthy... be hungrier... be blessed:
>
> > > > > > > > >http://TheWellnessFoundation.com/PressRelease
>
> > > > > > > > Greetings!!
>
> > > > > > > Hi :-)
>
> > > > > > > >, Why can't body get physiological tolerances or resistance
> > > > > > > > to increased insulin's exposure secreted due to persisting higher
> > > > > > > > glucose levels in IR cases?
>
> > > > > > > It simply is not what is happening.
>
> > > > > > How/why downregulation of insulin's receptors take place?
>
> > > > > Pro-inflammatory cytokines from VAT cause the impairment of insulin
> > > > > response at both the receptor and signalling levels.
> > > > Whether VAT or its inflammatory response is a signal of excessive
> > > > availabilty of energy stores, on which body's mechanism are active to
> > > > reverse?
> > > > > > > > Excessive fats can also be an expression
> > > > > > > > of excessive energy available, so may cause mecanisms to balance
> > > > > > > > these, one may be such inflamatory response?
>
> > > > > > > It is simply the nature of the bad "inside" fat (visceral adipose
> > > > > > > tissue or VAT) to be completely pathological.
>
> > > > > > Do VATS not provide insulation, increased transcapillary movements and
> > > > > > energy?
>
> > > > > VAT is not SAT.
>
> > > > VAT may be an insulation to viscera/organs?
>
> > > It is not. ?Organs have visceral pleura to serve as "insulation."
>
> > Additional isulation and to hold visceral pleura?
> > What can cause, organs to get additional insulation?> > Immediate energy can be
> > > > released on utilizing these and I think inflammatory responses are
> > > > related to increased transcapillarry movements?
>
> > ?Insulin's one action is to enhance transcapillary movements by
> > relaxing vascular tone?> Fat does not serve as immediate energy.
>
> > Earlier than energy from SAT, if glucose is less efficient due to IR?> The inflammation promoted by VAT serves only to cause harm.
>
> > Can our body need such inflammation for any purpose?
>
> > > May GOD bless you in HIS mighty way making you healthier (hungrier)
> > > than ever:
> > Thanks.
> > >http://HeartMDPhD.com/HolySpirit/PressRelease
>
> > > Prayerfully in Jesus' awesome love,
>
> > > Andrew <><
> > > --
> > > Andrew B. Chung, MD/PhD
> > > Cardiologist- Hide quoted text -
>
> > > - Show quoted text -- Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> > - Show quoted text -
>
> Kumar: I should remind you that the issue of VAT is not relevant so
> much to all types of T2 diabetes. As you know T2 is a heterogenous
> disease mostly (80%) VAT related but there are other issues to address
> in treating this disease. Fat is just part of the problem in some
> patients.
>
> Larry- Hide quoted text -
>
> - Show quoted text -

Sometime I become bit suspicious, whether this is a disease or just an
instability.

On Aug 25, 1:30 pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> Larry wrote:
> > Convicted friend Kumar <lordshiva5...@gmail.com> wrote:
> > > Andrew, in the Holy Spirit, boldly wrote:
> > Kumar: I should remind you that the issue of VAT is not relevant so
> > much to all types of T2 diabetes.
>
> By definition, type-2 diabetes is a problem of insulin resistance that
> is complicated by secondary pancreatic (beta islet cell)
> insufficiency.
>
> It is also known that VAT is the cause of insulin resistance (IR/
> MetS).
>
> It logically follows that VAT is relevant to every instance of type-2
> diabetes.
>
> Indeed, there is VAT present in every instance of type-2 diabetes.
>
> > As you know T2 is a heterogenous disease
>
> Not where IR/MetS is concerned.
>
> > mostly (80%) VAT related
>
> IR/MetS is 100% VAT related.
>
> > but there are other issues to address
> > in treating this disease.
>
> Only while addressing the cause in hopes of achieving a cure.
>
> > Fat is just part of the problem in some
> > patients.
>
> VAT is not just fat... it is the bad "inside" fat that is completely
> pathological, where only a few ounces can confer IR/MetS.
>
> Folks with IR/MetS invariably have large WHRs (Waist to Hip Ratios):
Not all folks with diabetes2 have large WHRs. ??

There can be hyperglycemia either due to hyperenergy state in body or
some resistance to get needed energy from energy stores. I think,
higher insulin can resist energy stores usage.
> Greater than 0.75 (women).
>
> Greater than 0.85 (men).
>
> Be hungry... be healthy... be hungrier... be blessed:
>
> http://TheWellnessFoundation.com/PressRelease

> Prayerfully in Jesus' awesome love,
>
> Andrew <><
> --
> Andrew B. Chung, MD/PhD
> Cardiologist- Hide quoted text -
>
> - Show quoted text -

convicted friend Kumar wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> > Larry wrote:
> > > Convicted friend Kumar <lordshiva5...@gmail.com> wrote:
> > > > Andrew, in the Holy Spirit, boldly wrote:
> > > Kumar: I should remind you that the issue of VAT is not relevant so
> > > much to all types of T2 diabetes.
> >
> > By definition, type-2 diabetes is a problem of insulin resistance that
> > is complicated by secondary pancreatic (beta islet cell)
> > insufficiency.
> >
> > It is also known that VAT is the cause of insulin resistance (IR/
> > MetS).
> >
> > It logically follows that VAT is relevant to every instance of type-2
> > diabetes.
> >
> > Indeed, there is VAT present in every instance of type-2 diabetes.
> >
> > > As you know T2 is a heterogenous disease
> >
> > Not where IR/MetS is concerned.
> >
> > > mostly (80%) VAT related
> >
> > IR/MetS is 100% VAT related.
> >
> > > but there are other issues to address
> > > in treating this disease.
> >
> > Only while addressing the cause in hopes of achieving a cure.
> >
> > > Fat is just part of the problem in some
> > > patients.
> >
> > VAT is not just fat... it is the bad "inside" fat that is completely
> > pathological, where only a few ounces can confer IR/MetS.
> >
> > Folks with IR/MetS invariably have large WHRs (Waist to Hip Ratios):
>
> Not all folks with diabetes2 have large WHRs. ??

**All** folks with type-2 diabetes have had large WHRs at the time of
diagnosis as defined by:

Greater than 0.75 (females).

Greater than 0.85 (males).

There have been no exceptions.

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologisttext -

On Aug 25, 3:14 pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> convicted friend Kumar wrote:
> > Andrew, in the Holy Spirit, boldly wrote:
> > > Larry wrote:
> > > > Convicted friend Kumar <lordshiva5...@gmail.com> wrote:
> > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > Kumar: I should remind you that the issue of VAT is not relevant so
> > > > much to all types of T2 diabetes.
>
> > > By definition, type-2 diabetes is a problem of insulin resistance that
> > > is complicated by secondary pancreatic (beta islet cell)
> > > insufficiency.
>
> > > It is also known that VAT is the cause of insulin resistance (IR/
> > > MetS).
>
> > > It logically follows that VAT is relevant to every instance of type-2
> > > diabetes.
>
> > > Indeed, there is VAT present in every instance of type-2 diabetes.
>
> > > > As you know T2 is a heterogenous disease
>
> > > Not where IR/MetS is concerned.
>
> > > > mostly (80%) VAT related
>
> > > IR/MetS is 100% VAT related.
>
> > > > but there are other issues to address
> > > > in treating this disease.
>
> > > Only while addressing the cause in hopes of achieving a cure.
>
> > > > Fat is just part of the problem in some
> > > > patients.
>
> > > VAT is not just fat... it is the bad "inside" fat that is completely
> > > pathological, where only a few ounces can confer IR/MetS.
>
> > > Folks with IR/MetS invariably have large WHRs (Waist to Hip Ratios):
>
> > Not all folks with diabetes2 have large WHRs. ??
>
> **All** folks with type-2 diabetes have had large WHRs at the time of
> diagnosis as defined by:
>
> Greater than 0.75 (females).
>
> Greater than 0.85 (males).
>
> There have been no exceptions.
Sorry, few of my nearones are not?

" Oxidation May Be New Blood Pressure Regulator
http://www.medicalnewstoday.com/articles/80602.php"

Whether vat related inflammation will be doing above?

> Be hungry... be healthy... be hungrier... be blessed:
>
> http://TheWellnessFoundation.com/PressRelease
>
> Prayerfully in Jesus' awesome love,
>
> Andrew <><
> --
> Andrew B. Chung, MD/PhD
> Cardiologisttext -- Hide quoted text -
>
> - Show quoted text -

convicted friend Kumar wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> > convicted friend Kumar wrote:
> > > Andrew, in the Holy Spirit, boldly wrote:
> > > > Larry wrote:
> > > > > Convicted friend Kumar <lordshiva5...@gmail.com> wrote:
> > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > Kumar: I should remind you that the issue of VAT is not relevant so
> > > > > much to all types of T2 diabetes.
> >
> > > > By definition, type-2 diabetes is a problem of insulin resistance that
> > > > is complicated by secondary pancreatic (beta islet cell)
> > > > insufficiency.
> >
> > > > It is also known that VAT is the cause of insulin resistance (IR/
> > > > MetS).
> >
> > > > It logically follows that VAT is relevant to every instance of type-2
> > > > diabetes.
> >
> > > > Indeed, there is VAT present in every instance of type-2 diabetes.
> >
> > > > > As you know T2 is a heterogenous disease
> >
> > > > Not where IR/MetS is concerned.
> >
> > > > > mostly (80%) VAT related
> >
> > > > IR/MetS is 100% VAT related.
> >
> > > > > but there are other issues to address
> > > > > in treating this disease.
> >
> > > > Only while addressing the cause in hopes of achieving a cure.
> >
> > > > > Fat is just part of the problem in some
> > > > > patients.
> >
> > > > VAT is not just fat... it is the bad "inside" fat that is completely
> > > > pathological, where only a few ounces can confer IR/MetS.
> >
> > > > Folks with IR/MetS invariably have large WHRs (Waist to Hip Ratios):
> >
> > > Not all folks with diabetes2 have large WHRs. ??
> >
> > **All** folks with type-2 diabetes have had large WHRs at the time of
> > diagnosis as defined by:
> >
> > Greater than 0.75 (females).
> >
> > Greater than 0.85 (males).
> >
> > There have been no exceptions.
>
> Sorry, few of my nearones are not?

No exceptions.

> " Oxidation May Be New Blood Pressure Regulator
> http://www.medicalnewstoday.com/articles/80602.php"
>
> Whether vat related inflammation will be doing above?

No.

> > Be hungry... be healthy... be hungrier... be blessed:
> >
> > http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

On Aug 26, 1:31 pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> convicted friend Kumar wrote:
> > Andrew, in the Holy Spirit, boldly wrote:
> > > convicted friend Kumar wrote:
> > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > Larry wrote:
> > > > > > Convicted friend Kumar <lordshiva5...@gmail.com> wrote:
> > > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > Kumar: I should remind you that the issue of VAT is not relevant so
> > > > > > much to all types of T2 diabetes.
>
> > > > > By definition, type-2 diabetes is a problem of insulin resistance that
> > > > > is complicated by secondary pancreatic (beta islet cell)
> > > > > insufficiency.
>
> > > > > It is also known that VAT is the cause of insulin resistance (IR/
> > > > > MetS).
>
> > > > > It logically follows that VAT is relevant to every instance of type-2
> > > > > diabetes.
>
> > > > > Indeed, there is VAT present in every instance of type-2 diabetes.
>
> > > > > > As you know T2 is a heterogenous disease
>
> > > > > Not where IR/MetS is concerned.
>
> > > > > > mostly (80%) VAT related
>
> > > > > IR/MetS is 100% VAT related.
>
> > > > > > but there are other issues to address
> > > > > > in treating this disease.
>
> > > > > Only while addressing the cause in hopes of achieving a cure.
>
> > > > > > Fat is just part of the problem in some
> > > > > > patients.
>
> > > > > VAT is not just fat... it is the bad "inside" fat that is completely
> > > > > pathological, where only a few ounces can confer IR/MetS.
>
> > > > > Folks with IR/MetS invariably have large WHRs (Waist to Hip Ratios):
>
> > > > Not all folks with diabetes2 have large WHRs. ??
>
> > > **All** folks with type-2 diabetes have had large WHRs at the time of
> > > diagnosis as defined by:
>
> > > Greater than 0.75 (females).
>
> > > Greater than 0.85 (males).
>
> > > There have been no exceptions.
>
> > Sorry, few of my nearones are not?
>
> No exceptions.
>
> > " Oxidation May Be New Blood Pressure Regulator
> >http://www.medicalnewstoday.com/articles/80602.php"
>
> > Whether vat related inflammation will be doing above?
>
> No.
Why not? Whether systemic inflammation is not vasodilatory and
effecting transcapillary movements?

In such sense, whether calcium instability can cause shortness of
breath by its vasoconstricting effect?
> > > Be hungry... be healthy... be hungrier... be blessed:
>
> > >http://TheWellnessFoundation.com/PressRelease
>
> Prayerfully in Jesus' awesome love,
>
> Andrew <><
> --
> Andrew B. Chung, MD/PhD
> Cardiologist- Hide quoted text -
>
> - Show quoted text -

convicted friend Kumar wrote:
> Andrew, in the Holy Spirit, boldly wrote:
> > convicted friend Kumar wrote:
> > > Andrew, in the Holy Spirit, boldly wrote:
> > > > convicted friend Kumar wrote:
> > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > Larry wrote:
> > > > > > > Convicted friend Kumar <lordshiva5...@gmail.com> wrote:
> > > > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > Kumar: I should remind you that the issue of VAT is not relevant so
> > > > > > > much to all types of T2 diabetes.
> >
> > > > > > By definition, type-2 diabetes is a problem of insulin resistance that
> > > > > > is complicated by secondary pancreatic (beta islet cell)
> > > > > > insufficiency.
> >
> > > > > > It is also known that VAT is the cause of insulin resistance (IR/
> > > > > > MetS).
> >
> > > > > > It logically follows that VAT is relevant to every instance of type-2
> > > > > > diabetes.
> >
> > > > > > Indeed, there is VAT present in every instance of type-2 diabetes.
> >
> > > > > > > As you know T2 is a heterogenous disease
> >
> > > > > > Not where IR/MetS is concerned.
> >
> > > > > > > mostly (80%) VAT related
> >
> > > > > > IR/MetS is 100% VAT related.
> >
> > > > > > > but there are other issues to address
> > > > > > > in treating this disease.
> >
> > > > > > Only while addressing the cause in hopes of achieving a cure.
> >
> > > > > > > Fat is just part of the problem in some
> > > > > > > patients.
> >
> > > > > > VAT is not just fat... it is the bad "inside" fat that is completely
> > > > > > pathological, where only a few ounces can confer IR/MetS.
> >
> > > > > > Folks with IR/MetS invariably have large WHRs (Waist to Hip Ratios):
> >
> > > > > Not all folks with diabetes2 have large WHRs. ??
> >
> > > > **All** folks with type-2 diabetes have had large WHRs at the time of
> > > > diagnosis as defined by:
> >
> > > > Greater than 0.75 (females).
> >
> > > > Greater than 0.85 (males).
> >
> > > > There have been no exceptions.
> >
> > > Sorry, few of my nearones are not?
> >
> > No exceptions.
> >
> > > " Oxidation May Be New Blood Pressure Regulator
> > >http://www.medicalnewstoday.com/articles/80602.php"
> >
> > > Whether vat related inflammation will be doing above?
> >
> > No.
>
> Why not?

http://SecondLaw.com

VAT is bad.

Truly, it is only when we are hungry (stomachs laughing and singing)
that our bodies get rid of the VAT.

Hunger is wonderful.

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist

On Aug 25, 2:48?am, Kumar <lordshiva5...@gmail.com> wrote:
> On Aug 25, 8:12 am, Larry <boelk...@aol.com> wrote:
>
>
>
>
>
> > On Aug 24, 7:58?pm, Kumar <lordshiva5...@gmail.com> wrote:
>
> > > On Aug 24, 4:16?pm, "Andrew B. Chung, MD/PhD"
>
> > > <heartdo...@emorycardiology.com> wrote:
> > > > convicted neighbor Kumar wrote:
> > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > convicted friend Kumar wrote:
> > > > > > > Andrew, in the Holy Spirit, boldly wrote:
> > > > > > > > convicted friend Kumar wrote:
> > > > > > > > >