Recovering from hypoglycemia

http://diabetes.org/tipoftheday.jsp?...s=233521549807

Question:
How long does it take me to recover from an episode of severe
hypoglycemia?

Answer:
Low blood glucose levels can affect your ability to think clearly,
because your brain does not work normally when it's not receiving
enough glucose. The good news is that your brain function usually
returns to normal after your low blood glucose is treated. Studies
have shown that if you're practicing intensive diabetes management,
frequent hypoglycemia does not cause any permanent brain damage.
Researchers recently studied brain function before and after severe
hypoglycemia. They found that brain function generally returns to
normal within 36 hours of a severe hypoglycemic attack. However, they
also found that patients with frequent hypoglycemia were more likely
to suffer from extreme mood changes, such as depression, though
whether or not frequent hypoglycemia causes these changes is still
unclear. You should also be aware that prolonged or severe
hypoglycemia that is untreated can cause permanent brain damage or
lead to a coma.

On 26 May 2007 18:06:22 -0700, Kurt wrote:

> http://diabetes.org/tipoftheday.jsp?...s=233521549807
>
> Question:
> How long does it take me to recover from an episode of severe
> hypoglycemia?
>
> Answer:
> Low blood glucose levels can affect your ability to think clearly,
> because your brain does not work normally when it's not receiving
> enough glucose. The good news is that your brain function usually
> returns to normal after your low blood glucose is treated. Studies
> have shown that if you're practicing intensive diabetes management,
> frequent hypoglycemia does not cause any permanent brain damage.
> Researchers recently studied brain function before and after severe
> hypoglycemia. They found that brain function generally returns to
> normal within 36 hours of a severe hypoglycemic attack. However, they
> also found that patients with frequent hypoglycemia were more likely
> to suffer from extreme mood changes, such as depression, though
> whether or not frequent hypoglycemia causes these changes is still
> unclear. You should also be aware that prolonged or severe
> hypoglycemia that is untreated can cause permanent brain damage or
> lead to a coma.

I have been having trouble with lows. (1x5 gylburide and 2x500 metformin)
It seemd my BG creeps down in the afternoon-I think I had better start some
kind of snack routine. I feel OK, no more confused than usual :-) I was a
little upset when I hit 2.7 or 48.6 2 hours after supper yesterday. My
doctor friend said that the glyburide hits it's peak about 4 hours after
taking, which would be around 12:30 1 PM most days. I will see what the
family doc says, and of course value all of your opinions.

Here's what's happening:

1 1782 5/21/2007 10:20:00 AM 5.2 before breakfas
1 1783 5/21/2007 4:40:00 PM 5.6
1 1784 5/21/2007 10:24:00 PM 7.5 2 hours after s
1 1785 5/22/2007 8:30:00 AM 5.8 before breakfas
1 1786 5/22/2007 9:00:00 PM 5.4 1 hour after su
1 1787 5/23/2007 8:15:00 AM 5.1 before breakfas
1 1788 5/23/2007 6:40:00 PM 3.3 before supper
1 1789 5/23/2007 7:40:00 PM 6 1 hour after su
1 1790 5/24/2007 8:15:00 AM 5.2 before breakfas
1 1791 5/24/2007 8:45:00 PM 4.9 before supper
1 1792 5/25/2007 8:25:00 AM 4.8 before breakfas
1 1793 5/25/2007 6:30:00 PM 4.2 before supper
1 1794 5/25/2007 10:00:00 PM 2.7 2 hours after s
1 1795 5/25/2007 10:40:00 PM 6.7
1 1796 5/26/2007 12:21:00 AM 5.7
1 1797 5/26/2007 8:45:00 AM 4.8 before breakfas
1 1798 5/26/2007 8:25:00 PM 5.3 1 hour after su
1 1799 5/26/2007 1:43:00 PM 3.8
1 1800 5/26/2007 5:51:00 PM 2.9 before supper
1 1801 5/26/2007 10:23:00 PM 6.3

Thx;

bobd

On May 26, 10:36 pm, bobd <mer...@videotron.ca> wrote:
> On 26 May 2007 18:06:22 -0700, Kurt wrote:
>
>
>
>
>
> >http://diabetes.org/tipoftheday.jsp?...theday&vms=233...
>
> > Question:
> > How long does it take me to recover from an episode of severe
> > hypoglycemia?
>
> > Answer:
> > Low blood glucose levels can affect your ability to think clearly,
> > because your brain does not work normally when it's not receiving
> > enough glucose. The good news is that your brain function usually
> > returns to normal after your low blood glucose is treated. Studies
> > have shown that if you're practicing intensive diabetes management,
> > frequent hypoglycemia does not cause any permanent brain damage.
> > Researchers recently studied brain function before and after severe
> > hypoglycemia. They found that brain function generally returns to
> > normal within 36 hours of a severe hypoglycemic attack. However, they
> > also found that patients with frequent hypoglycemia were more likely
> > to suffer from extreme mood changes, such as depression, though
> > whether or not frequent hypoglycemia causes these changes is still
> > unclear. You should also be aware that prolonged or severe
> > hypoglycemia that is untreated can cause permanent brain damage or
> > lead to a coma.
>
> I have been having trouble with lows. (1x5 gylburide and 2x500 metformin)
> It seemd my BG creeps down in the afternoon-I think I had better start some
> kind of snack routine. I feel OK, no more confused than usual :-) I was a
> little upset when I hit 2.7 or 48.6 2 hours after supper yesterday. My
> doctor friend said that the glyburide hits it's peak about 4 hours after
> taking, which would be around 12:30 1 PM most days. I will see what the
> family doc says, and of course value all of your opinions.
>
> Here's what's happening:
>
> 1 1782 5/21/2007 10:20:00 AM 5.2 before breakfas
> 1 1783 5/21/2007 4:40:00 PM 5.6
> 1 1784 5/21/2007 10:24:00 PM 7.5 2 hours after s
> 1 1785 5/22/2007 8:30:00 AM 5.8 before breakfas
> 1 1786 5/22/2007 9:00:00 PM 5.4 1 hour after su
> 1 1787 5/23/2007 8:15:00 AM 5.1 before breakfas
> 1 1788 5/23/2007 6:40:00 PM 3.3 before supper
> 1 1789 5/23/2007 7:40:00 PM 6 1 hour after su
> 1 1790 5/24/2007 8:15:00 AM 5.2 before breakfas
> 1 1791 5/24/2007 8:45:00 PM 4.9 before supper
> 1 1792 5/25/2007 8:25:00 AM 4.8 before breakfas
> 1 1793 5/25/2007 6:30:00 PM 4.2 before supper
> 1 1794 5/25/2007 10:00:00 PM 2.7 2 hours after s
> 1 1795 5/25/2007 10:40:00 PM 6.7
> 1 1796 5/26/2007 12:21:00 AM 5.7
> 1 1797 5/26/2007 8:45:00 AM 4.8 before breakfas
> 1 1798 5/26/2007 8:25:00 PM 5.3 1 hour after su
> 1 1799 5/26/2007 1:43:00 PM 3.8
> 1 1800 5/26/2007 5:51:00 PM 2.9 before supper
> 1 1801 5/26/2007 10:23:00 PM 6.3
>
> Thx;
>
> bobd - Hide quoted text -
>
> - Show quoted text -

Thats nice.

[[ This message was both posted and mailed: see
the "To," "Cc," and "Newsgroups" headers for details. ]]

In article <s4606rf4y3zy$.1au9ub3ojkdhs.dlg@40tude.net>, bobd
<mervin@videotron.ca> wrote:

> 1x5 gylburide

FWIW I am 2 x 2.5 glyburide taken before breakfast, and before dinner.

Original instructions were to split the 5 mg pill and take the halves
before breakfast and dinner.

Pharmacist issued 2.5 mg pills instead of the 5 mg pill upon reading
the prescription. No problems with lows, YMMV.

--
To reply, substitute .com for .invalid in address, i.e., john.101a (at)
*yahoo.com

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the "To," "Cc," and "Newsgroups" headers for details. ]]

From http://www.peru.k12.in.us/PJHS/Teach...200/glybur.htm

4. DOSAGE INTERVAL
Once-a-day therapy is usually satisfactory, based upon usual meal
patterns and a 10 hour half-life of Glyburide. Some patients,
particularly those receiving more than 10 mg daily, may have a more
satisfactory response with twice-a-day dosage.

--
To reply, substitute .com for .invalid in address, i.e., john.101a (at)
*yahoo.com

On Sat, 26 May 2007 22:36:13 -0400, bobd <mervin@videotron.ca> wrote:

>I have been having trouble with lows. (1x5 gylburide and 2x500 metformin)
>It seemd my BG creeps down in the afternoon-I think I had better start some
>kind of snack routine. I feel OK, no more confused than usual :-) I was a
>little upset when I hit 2.7 or 48.6 2 hours after supper yesterday. My
>doctor friend said that the glyburide hits it's peak about 4 hours after
>taking, which would be around 12:30 1 PM most days. I will see what the
>family doc says, and of course value all of your opinions.

I wonder if you still need all that glyburide. John's suggestion for
splitting them is interesting...

I generally don't like the idea of sulphs, though; I can't see the
point in flogging dead beta cells to produce extra insulin,
particularly as you're getting lows. If it were me, I'd rather up the
metformin dose to tackle insulin resistance than take the glyburide.

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.5% BMI 25

However, each episode of hypoglycemia can trigger coronary plaque
rupture leading to acute coronary syndrome (ie heart attack).

May GOD bless you in HIS mighty way.

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
http://EmoryCardiology.com

"Unlike the 2PD-OMER Approach, weight loss diets can't be combined
with well-balanced diets."
http://HeartMDPhD.com/Love/TheTruth


Kurt wrote:
> http://diabetes.org/tipoftheday.jsp?...s=233521549807
>
> Question:
> How long does it take me to recover from an episode of severe
> hypoglycemia?
>
> Answer:
> Low blood glucose levels can affect your ability to think clearly,
> because your brain does not work normally when it's not receiving
> enough glucose. The good news is that your brain function usually
> returns to normal after your low blood glucose is treated. Studies
> have shown that if you're practicing intensive diabetes management,
> frequent hypoglycemia does not cause any permanent brain damage.
> Researchers recently studied brain function before and after severe
> hypoglycemia. They found that brain function generally returns to
> normal within 36 hours of a severe hypoglycemic attack. However, they
> also found that patients with frequent hypoglycemia were more likely
> to suffer from extreme mood changes, such as depression, though
> whether or not frequent hypoglycemia causes these changes is still
> unclear. You should also be aware that prolonged or severe
> hypoglycemia that is untreated can cause permanent brain damage or
> lead to a coma.

Nicky <ukc802466929@btconnect.com> wrote:
: On Sat, 26 May 2007 22:36:13 -0400, bobd <mervin@videotron.ca> wrote:

: >I have been having trouble with lows. (1x5 gylburide and 2x500 metformin)
: >It seemd my BG creeps down in the afternoon-I think I had better start some
: >kind of snack routine. I feel OK, no more confused than usual :-) I was a
: >little upset when I hit 2.7 or 48.6 2 hours after supper yesterday. My
: >doctor friend said that the glyburide hits it's peak about 4 hours after
: >taking, which would be around 12:30 1 PM most days. I will see what the
: >family doc says, and of course value all of your opinions.

: I wonder if you still need all that glyburide. John's suggestion for
: splitting them is interesting...

: I generally don't like the idea of sulphs, though; I can't see the
: point in flogging dead beta cells to produce extra insulin,
: particularly as you're getting lows. If it were me, I'd rather up the
: metformin dose to tackle insulin resistance than take the glyburide.

: Nicky.

Do you eat lunch? As your before dinner numbers are often so low, it
might mean you need, eiter to eat lunch, or idf you do already, take a
small a fternoon snack.

Nicky's thought about the amount of glyburide sounds right to me too.

Wendy

On Sun, 27 May 2007 15:54:10 +0000 (UTC), W. Baker wrote:

> Nicky <ukc802466929@btconnect.com> wrote:
>: On Sat, 26 May 2007 22:36:13 -0400, bobd <mervin@videotron.ca> wrote:
>
>:>I have been having trouble with lows. (1x5 gylburide and 2x500 metformin)
>:>It seemd my BG creeps down in the afternoon-I think I had better start some
>:>kind of snack routine. I feel OK, no more confused than usual :-) I was a
>:>little upset when I hit 2.7 or 48.6 2 hours after supper yesterday. My
>:>doctor friend said that the glyburide hits it's peak about 4 hours after
>:>taking, which would be around 12:30 1 PM most days. I will see what the
>:>family doc says, and of course value all of your opinions.
>
>: I wonder if you still need all that glyburide. John's suggestion for
>: splitting them is interesting...
>
>: I generally don't like the idea of sulphs, though; I can't see the
>: point in flogging dead beta cells to produce extra insulin,
>: particularly as you're getting lows. If it were me, I'd rather up the
>: metformin dose to tackle insulin resistance than take the glyburide.
>
>: Nicky.
>
> Do you eat lunch? As your before dinner numbers are often so low, it
> might mean you need, eiter to eat lunch, or idf you do already, take a
> small a fternoon snack.
>
> Nicky's thought about the amount of glyburide sounds right to me too.
>
> Wendy

Thanks to all for the counsel. Yes I do eat lunch, but sometimes not till
2-3 PM some days. I am going to change this to earlier, and add the snack.
I tried the half pill this morning, and forgot to take a metformin at
supper and here is what today was like:

5.4 or 90 before breakfast
6.3 or 112 before supper
4.7 at 9:20 PM

Snack of 2 toast with marmalade and waffle with cream cheese after the 4.7.
Also, I have been adding a desert since I saw those lows, really not
holding back, actually. Still learning. I thinkI respond pretty well to
the addition of 1/2 hour brisk walk every morning, and no more sugar
snacks.

See you later, and thanks;

bobd

bobd <mervin@videotron.ca> wrote:
: On Sun, 27 May 2007 15:54:10 +0000 (UTC), W. Baker wrote:

: > Nicky <ukc802466929@btconnect.com> wrote:
: >: On Sat, 26 May 2007 22:36:13 -0400, bobd <mervin@videotron.ca> wrote:
: >
: >:>I have been having trouble with lows. (1x5 gylburide and 2x500 metformin)
: >:>It seemd my BG creeps down in the afternoon-I think I had better start some
: >:>kind of snack routine. I feel OK, no more confused than usual :-) I was a
: >:>little upset when I hit 2.7 or 48.6 2 hours after supper yesterday. My
: >:>doctor friend said that the glyburide hits it's peak about 4 hours after
: >:>taking, which would be around 12:30 1 PM most days. I will see what the
: >:>family doc says, and of course value all of your opinions.
: >
: >: I wonder if you still need all that glyburide. John's suggestion for
: >: splitting them is interesting...
: >
: >: I generally don't like the idea of sulphs, though; I can't see the
: >: point in flogging dead beta cells to produce extra insulin,
: >: particularly as you're getting lows. If it were me, I'd rather up the
: >: metformin dose to tackle insulin resistance than take the glyburide.
: >
: >: Nicky.
: >
: > Do you eat lunch? As your before dinner numbers are often so low, it
: > might mean you need, eiter to eat lunch, or idf you do already, take a
: > small a fternoon snack.
: >
: > Nicky's thought about the amount of glyburide sounds right to me too.
: >
: > Wendy

: Thanks to all for the counsel. Yes I do eat lunch, but sometimes not till
: 2-3 PM some days. I am going to change this to earlier, and add the snack.
: I tried the half pill this morning, and forgot to take a metformin at
: supper and here is what today was like:

: 5.4 or 90 before breakfast
: 6.3 or 112 before supper
: 4.7 at 9:20 PM

: Snack of 2 toast with marmalade and waffle with cream cheese after the 4.7.
: Also, I have been adding a desert since I saw those lows, really not
: holding back, actually. Still learning. I thinkI respond pretty well to
: the addition of 1/2 hour brisk walk every morning, and no more sugar
: snacks.

: See you later, and thanks;

: bobd

Wow! That is some snack, carbwise. Only the cream cheese is not a fast
acting carb. tht woudl send me spiking to the moon!!! I assume, as you
didn't specify, that the marmalade was regula sugar swetened stuff and the
waffle a regular one, not some kind of reduced carb home made kind.
How long ws it between the snack and your dinner? If not much more than 2
hours, then I would think you are taking too much glyburide, which is
pushing out more insulin than you need adn unnecessarily working the beta
cells. I don't know if you have a issue with weight, but having to eat
that many extra calories for a snack to prevent a low would be difficult
if you are tryng to control or loose weight. It is called havignto eat
to your meds, which is not a great idea.

Good luck to you on getting all this worked out, and keep us informed. We
are not Docs, but have much cumulative experience here tht might help you.

Wendy

On Mon, 28 May 2007 15:29:18 +0000 (UTC), W. Baker wrote:

> bobd <mervin@videotron.ca> wrote:
>: On Sun, 27 May 2007 15:54:10 +0000 (UTC), W. Baker wrote:
>
>:> Nicky <ukc802466929@btconnect.com> wrote:
>:>: On Sat, 26 May 2007 22:36:13 -0400, bobd <mervin@videotron.ca> wrote:
>:>
>:>:>I have been having trouble with lows. (1x5 gylburide and 2x500 metformin)
>:>:>It seemd my BG creeps down in the afternoon-I think I had better start some
>:>:>kind of snack routine. I feel OK, no more confused than usual :-) I was a
>:>:>little upset when I hit 2.7 or 48.6 2 hours after supper yesterday. My
>:>:>doctor friend said that the glyburide hits it's peak about 4 hours after
>:>:>taking, which would be around 12:30 1 PM most days. I will see what the
>:>:>family doc says, and of course value all of your opinions.
>:>
>:>: I wonder if you still need all that glyburide. John's suggestion for
>:>: splitting them is interesting...
>:>
>:>: I generally don't like the idea of sulphs, though; I can't see the
>:>: point in flogging dead beta cells to produce extra insulin,
>:>: particularly as you're getting lows. If it were me, I'd rather up the
>:>: metformin dose to tackle insulin resistance than take the glyburide.
>:>
>:>: Nicky.
>:>
>:> Do you eat lunch? As your before dinner numbers are often so low, it
>:> might mean you need, eiter to eat lunch, or idf you do already, take a
>:> small a fternoon snack.
>:>
>:> Nicky's thought about the amount of glyburide sounds right to me too.
>:>
>:> Wendy
>
>: Thanks to all for the counsel. Yes I do eat lunch, but sometimes not till
>: 2-3 PM some days. I am going to change this to earlier, and add the snack.
>: I tried the half pill this morning, and forgot to take a metformin at
>: supper and here is what today was like:
>
>: 5.4 or 90 before breakfast
>: 6.3 or 112 before supper
>: 4.7 at 9:20 PM
>
>: Snack of 2 toast with marmalade and waffle with cream cheese after the 4.7.
>: Also, I have been adding a desert since I saw those lows, really not
>: holding back, actually. Still learning. I thinkI respond pretty well to
>: the addition of 1/2 hour brisk walk every morning, and no more sugar
>: snacks.
>
>: See you later, and thanks;
>
>: bobd
>
> Wow! That is some snack, carbwise. Only the cream cheese is not a fast
> acting carb. tht woudl send me spiking to the moon!!! I assume, as you
> didn't specify, that the marmalade was regula sugar swetened stuff and the
> waffle a regular one, not some kind of reduced carb home made kind.
> How long ws it between the snack and your dinner? If not much more than 2
> hours, then I would think you are taking too much glyburide, which is
> pushing out more insulin than you need adn unnecessarily working the beta
> cells. I don't know if you have a issue with weight, but having to eat
> that many extra calories for a snack to prevent a low would be difficult
> if you are tryng to control or loose weight. It is called havignto eat
> to your meds, which is not a great idea.
>
> Good luck to you on getting all this worked out, and keep us informed. We
> are not Docs, but have much cumulative experience here tht might help you.
>
> Wendy

The snack put me up to 170 (9.5) before bed. Oops, that was my biggest
spike since diagnosis. Ya, that was all the regular stuff. BTW, this was
a day with 1/2 glyburide pill, and I forgot the metformin at supper. Then
this morning, I was back to 90 something (5.3). I am 6'4" 256 lbs, a
little round in the middle. I had thought about the eating to the meds
thing. I'll stick with the 1x5 glyburide till I see the doc.

Shucks, I KNOW I was low again today in the afternoon after having eaten an
early lunch. Just kind of felt it, ya know?

Thanks!

bobd

On Mon, 28 May 2007 23:33:33 -0400, bobd <mervin@videotron.ca> wrote:

>I'll stick with the 1x5 glyburide till I see the doc.

Hope that's not too long, Bob. Right now you don't sound like a safe
driving candidate...

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.5% BMI 25