Stroke risk doubles upon Type-2 diagnosis

http://stroke.ahajournals.org/cgi/co...full/38/6/1739

Background and Purpose— Cardiovascular risk factors are suboptimally treated
in diabetes, possibly because of the impression that there is a long delay
between diagnosis and the development of macrovascular complications such as
stroke. We determined the incidence of stroke in people newly treated for
type 2 diabetes.

Methods— We conducted an inception cohort study with the use of linked
administrative databases from Saskatchewan Health. Subjects entered the type
2 diabetes cohort on receipt of their first prescription for an oral
antidiabetic drug. We defined incident stroke as any hospital admission with
International Classification of Diseases, Ninth Revision, codes 430 to 438
inclusive. Age-standardized incidence rates were compared between the
diabetes cohort and the general population.

Results— There were 12 272 subjects in the diabetes cohort, the mean±SD age
was 64±13.6 years, and 55% were male. During a mean 5-year follow-up, 9.1%
of the diabetes cohort had a stroke. The age-standardized incidence rate for
stroke was 642 per 100 000 person-years in subjects with diabetes, compared
with 313 per 100 000 person-years in the general population (rate ratio=2.1,
95% CI=1.8 to 2.3). The relative short-term risk for stroke in the diabetes
cohort compared with the general population ranged from 1.8 (95%=CI 1.6 to
1.9) in persons >75 years to 5.6 (95% CI=2.5 to 9.3) in the 30- to 44-year
category.

Conclusions— The risk of stroke is high within 5 years of treatment for type
2 diabetes and more than double the rate for the general population. This
further supports the need for aggressive early cardiovascular risk factor
management in type 2 diabetes.
--
Jim Chinnis Warrenton, Virginia, USA

x-no-archive: yes

Jim Chinnis wrote:
> http://stroke.ahajournals.org/cgi/co...full/38/6/1739
>

So, then, we should all do what we can to avoid being diagnosed?? ;-)

Susan

Note that the group of newly diagnosed diabetics excludes those being
treated with diet and exercise. From the report, the diabetes cohort were
included if they had a prescription for a sulfonylurea or metformin and no
previous prescription, including for insulin, in the previous year.

Further, the study didn't adjust for risk factors such as BMI,
triglycerides, LDL, etc. Those correlate with diabetes, so the effect may be
at least partly due to factors other than diabetes.

....or the sulfonylureas...
--
Jim Chinnis Warrenton, Virginia, USA

In article <5dibkmF34gaj6U2@mid.individual.net>,
Susan <nevermind@nomail.com> wrote:

> x-no-archive: yes
>
> Jim Chinnis wrote:
> > http://stroke.ahajournals.org/cgi/co...full/38/6/1739
> >
>
> So, then, we should all do what we can to avoid being diagnosed?? ;-)
>
> Susan

I am most likely wrong. However I'd hazard a guess that blood sugar
(Glucose) is in the top 6 risk factors for many maladies. Number one
being quality of foods, 2 being a smoker or involved with soot in one
form or another, 3 being inactive, 4 being in a social nurturing
environment, 5 being the ability to know what Joy of life means.
I'd also suggest that these are not separate but have definite
interactions that are not easy to perceive . For example blood sugar and
exercise. Hugging you child when blood sugar is off. Yada Yada.

Care to add other's ?

Bill

--

S Jersey USA Zone 5 Shade
http://www.ocutech.com/ High tech Vison aid
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.

In news:5dibkmF34gaj6U2@mid.individual.net,
Susan (Sat, 16 Jun 2007 10:49:59 -0400) typed:
> x-no-archive: yes
>
> Jim Chinnis wrote:
>> http://stroke.ahajournals.org/cgi/co...full/38/6/1739
>>
>
> So, then, we should all do what we can to avoid being diagnosed?? ;-)

I wonder if it was do to the diabetic drugs? Or merely being told you
have diabetes? For me, I knew it was coming anyway. So I wasn't in shock
about it and I ignored it.

--
Bill
DX 1992 (ignored till 4/2007)
7R/7N 3x a day - Type II
A1c 11 (4/2007)
Acid-Reflex since 1992 - 20mg Omeprazole

On Sat, 16 Jun 2007 14:45:54 GMT, Jim Chinnis
<jchinnis@SPAMalum.mit.edu> wrote:

>http://stroke.ahajournals.org/cgi/co...full/38/6/1739

>Conclusions— The risk of stroke is high within 5 years of treatment for type
>2 diabetes

I'll try not to get any treatment then

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.5% BMI 25

Maybe my doctor will change his mind and tell me I'm not diabetic.

Jim this is the reason that doctors are advocating lower blood pressure
to try to prevent these strokes.

Loretta

sassybklynlady@webtv.net (Loretta Eisenberg) wrote in part:

>Jim this is the reason that doctors are advocating lower blood pressure
>to try to prevent these strokes.

Yes.

I had posted my comments on the abstract in a separate post that never made
it to my news server:

"Note that the group of newly diagnosed diabetics excludes those being
treated with diet and exercise. From the report, the diabetes cohort were
included if they had a prescription for a sulfonylurea or metformin and no
previous prescription, including for insulin, in the previous year.

"Further, the study didn't adjust for risk factors such as BMI,
triglycerides, LDL, etc. Those correlate with diabetes, so the effect may be
at least partly due to factors other than diabetes.

"...or the sulfonylureas..."
--
Jim Chinnis Warrenton, Virginia, USA