More on HT

More on the WHI study. I certainly regret taking *any* HT, even if it was
for only just over a year.

http://www.msnbc.msn.com/id/23468941/

http://www.eurekalert.org/pub_releas...-wfs022908.php

Peahen

x-no-archive: yes

Peahen wrote:
> More on the WHI study. I certainly regret taking *any* HT, even if it was
> for only just over a year.
>


Not I. I tried not to, couldn't live.

One thing that's not at all accounted for by the WHI is the fact that
oral estrogens have great impact on cortisol levels, which when elevated
raise mortality from all sorts of conditions, but transdermal estrogen
does not increase cortisol binding globulin at all.

Susan

"Susan" <nevermind@nomail.com> wrote in message
news:635vb6F266kapU2@mid.individual.net...
> x-no-archive: yes
>
> Peahen wrote:
>> More on the WHI study. I certainly regret taking *any* HT, even if it
>> was for only just over a year.
>>
>
>
> Not I. I tried not to, couldn't live.
>
> One thing that's not at all accounted for by the WHI is the fact that oral
> estrogens have great impact on cortisol levels, which when elevated raise
> mortality from all sorts of conditions, but transdermal estrogen does not
> increase cortisol binding globulin at all.
>
> Susan


A study devoted to transdermal hormones would be useful and, I'm sure,
appreciated.

The estradiol I took was oral. I was lucky enough to find out pretty
quickly that I didn't need it, although the doctor I dumped insisted my
memory would be better taking it.

Peahen

x-no-archive: yes

Peahen wrote:

> A study devoted to transdermal hormones would be useful and, I'm sure,
> appreciated.
>
> The estradiol I took was oral. I was lucky enough to find out pretty
> quickly that I didn't need it, although the doctor I dumped insisted my
> memory would be better taking it.

Good for you for dumping the dopey doc.

There's been so much focus on estrogen only vs. estrogen/progesterone.
No one is looking at the huge impact that oral vs. transdermal has on
the HPA axis, which rules everything, from immunity to blood glucose to
thyroid to stress response, etc.

Susan

"Peahen" <Peahen1955@gmail.com> wrote in message
news:fqkiaa$gd6$1@registered.motzarella.org...
>
>
> A study devoted to transdermal hormones would be useful and, I'm sure,
> appreciated.
-----------------
It would be greatly appreciated by me, for one. I got breast cancer while
using Premarin cream and can't help wondering if A triggered B.

Eva

On Mar 4, 5:32 pm, Susan <neverm...@nomail.com> wrote:
> x-no-archive: yes
>
> Peahen wrote:
> > A study devoted to transdermal hormones would be useful and, I'm sure,
> > appreciated.
>
> > The estradiol I took was oral. I was lucky enough to find out pretty
> > quickly that I didn't need it, although the doctor I dumped insisted my
> > memory would be better taking it.
>
> Good for you for dumping the dopey doc.
>
> There's been so much focus on estrogen only vs. estrogen/progesterone.
> No one is looking at the huge impact that oral vs. transdermal has on
> the HPA axis, which rules everything, from immunity to blood glucose to
> thyroid to stress response, etc.
>
> Susan

susan,

thanks for bringing this point up again. it really grinds me that
this hasn't been examined.

hope you are doing well these days.
ellen

On Mar 5, 7:47*am, ellen <epdps...@gmail.com> wrote:
> On Mar 4, 5:32 pm, Susan <neverm...@nomail.com> wrote:
>
>
>
>
>
> > x-no-archive: yes
>
> > Peahen wrote:
> > > A study devoted to transdermal hormones would be useful and, I'm sure,
> > > appreciated.
>
> > > The estradiol I took was oral. *I was lucky enough to find out pretty
> > > quickly that I didn't need it, although the doctor I dumped insisted my
> > > memory would be better taking it.
>
> > Good for you for dumping the dopey doc.
>
> > There's been so much focus on estrogen only vs. estrogen/progesterone.
> > No one is looking at the huge impact that oral vs. transdermal has on
> > the HPA axis, which rules everything, from immunity to blood glucose to
> > thyroid to stress response, etc.
>
> > Susan
>
> susan,
>
> thanks for bringing this point up again. *it really grinds me that
> this hasn't been examined.
>
> hope you are doing well these days.
> ellen- Hide quoted text -
>
> - Show quoted text -

I seem to recall that the WHI women with increased breast cancer risk
were taking full-strength premarin/progesterone for at least several
years. There are many alternatives to that. My initial hormone
prescription was big-time overkill. Our motto needs to be, the
smallest dose for the shortest length of time. Many clueless doctors
start out with high doses, which must be questioned. We have to
remember that doctors get kickbacks for prescribing certain drugs.
When a friend went to a doctor for depression, he idiotically tried
treating it with a walloping dose of Prempro!
If it makes sense to cut down hormone doses slowly, it also makes
sense to start out with a small dose and up it slowly if necessary.
It also makes sense to try weaning off every six months. Hard to
believe I know, but the vast majority of women do get past this stage
of life.
Les

x-no-archive: yes

sage hen wrote:

> I seem to recall that the WHI women with increased breast cancer risk
> were taking full-strength premarin/progesterone for at least several
> years. There are many alternatives to that. My initial hormone
> prescription was big-time overkill. Our motto needs to be, the
> smallest dose for the shortest length of time.

Yes, and transdermal, too, with studies to compare the outcome to oral.
Compounded hormones have an infinite range of dosages so that one isn't
taking the arbitrary doses mass produced for others with very different
needs.

Many clueless doctors
> start out with high doses, which must be questioned. We have to
> remember that doctors get kickbacks for prescribing certain drugs.
> When a friend went to a doctor for depression, he idiotically tried
> treating it with a walloping dose of Prempro!
> If it makes sense to cut down hormone doses slowly, it also makes
> sense to start out with a small dose and up it slowly if necessary.
> It also makes sense to try weaning off every six months. Hard to
> believe I know, but the vast majority of women do get past this stage
> of life.

Yep.

Susan

Determined to keep everything as natural as possible I had my mind set
on passing through menopause without hormone treatment but I have
recently found myself considering HRT options because of increasing
symptoms which are affecting my day to day life.

I am currently reading a book titled "Hormone Replacement - the real
truth" by Dr Sandra Cabot. It was written after the WHI study results
and offers comprehensive reading on hormone imbalances, hormone
testing and menopausal symptoms. It also has information on HRT
options and doses. It sees patches and creams as a safer alternative
to oral medication. There is a chapter relating to "the In and Outs
of Natural HRT".

It has been the most helpful book that I have read on menopause and
hormones : it may help other ladies in the group.

Jane_G

On Mar 5, 10:27*pm, free...@optusnet.com.au wrote:
> Determined to keep everything as natural as possible I had my mind set
> on passing through menopause without hormone treatment but I have
> recently found myself considering HRT options because of increasing
> symptoms which are affecting my day to day life.
>
> I am currently reading a book titled "Hormone Replacement - the real
> truth" by Dr Sandra Cabot. It was written after the WHI study results
> and offers *comprehensive reading on hormone imbalances, hormone
> testing and menopausal symptoms. It also has information on HRT
> options and doses. *It sees *patches and creams as a safer alternative
> to oral medication. *There is a chapter relating to "the In and Outs
> of Natural HRT".
>
> It has been the most helpful book that I have read on menopause and
> hormones : it may help other ladies in the group.
>
> Jane_G

Yes, Jane, my mind was made up for years that I'd never take HRT, but
my body had other plans. I'm still compelled to take hormones
responsibly--eschewing the cruelty of Premarin, taking the smallest
dose for the shortest possible time, and finding the least harmful
delivery method I can afford.

The website Survivor's Guide to Surgical Menopause has some
interesting info on alternatives to oral HRT (sorry guys, I'm computer-
illiterate and don't know how to give you a link). Under "Mechanics
of Using the Transbuccal Route for HRT" they say it's possible to take
micronized estradiol (generic Estrace) sublingually, thus bypassing
the digestive system. The author says this eliminates at least some
of the downside of oral estrogen delivery. There are disadvantages;
the dose is tricky, it's an off-label use, etc. The advantage is the
extremely low cost--less than $5 a month.

Has anyone ever tried this?

Les