<<snip>>
proves that routine iron supplementation in nonanaemic women is not
rational and may be harmful.
<<snip>>
BJOG. 2007 Jun;114(6):684-8.A randomised placebo-controlled trial to
determine the effect of iron supplementation on pregnancy outcome in
pregnant women with haemoglobin > or = 13.2 g/dl.Ziaei S, Norrozi M,
Faghihzadeh S, Jafarbegloo E.
Department of Obstetrics and Gynecology, Faculty of Medical Science,
Tarbiat Modarres University, Tehran, Iran.
ziaei_99@yahoo.com
OBJECTIVE: To study the effect of iron supplementation on pregnancy
outcome in pregnant women with haemoglobin (Hb) > or = 13.2 g/dl.
DESIGN: A randomised, double-blind, placebo-controlled trial. SETTING:
Routine health services. POPULATION: Seven hundred and twenty-seven
pregnant women with Hb > or = 13.2 g/dl in the early stage of the
second trimester. METHODS: Each woman took one tablet of 50 mg of
ferrous sulphate daily in the case group (n = 370) or placebo in the
control group (n = 357) throughout pregnancy. MAIN OUTCOME MEASURES:
Pregnancy outcome. RESULTS: While there were no significant
differences in demographic and obstetric characteristics between the
two groups before any intervention, small-for-gestational-age birth
rate and the number of women with hypertension disorder increased
significantly in the case group in comparison with the control group
(57 [15.7%] versus 36 [10.3%], P = 0.035, 10 [2.7%] versus 3 [8%], P =
0.05, respectively). CONCLUSIONS: Our finding proves that routine iron
supplementation in nonanaemic women is not rational and may be
harmful.
PMID: 17516958 [PubMed - in process]
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